CTSI-CN Awardees

2014

Pilot Research Awards for Faculties of Children’s National and George Washington University (Cycle XIII)

Anne Chiaramello George Washington University A Novel Epigenetic and Metabolic Approach for the Pediatric Mitochondrial Disease MELAS
Niti Dham Children's National Early Detection of Cardiac Toxicity in Childhood Cancer Survivors
Yaser Diab Children's National High on-Aspirin Platelet Reactivity /Aspirin Resistance in Children Undergoing Fontan Palliation for Single Ventricle Physiology
Rohan Fernandes Children's National Prussian blue nanoparticles for laser-induced photothermal therapy of neuroblastomas
Michael Keller Children's National Adoptive immunotherapy for Treatment of Viral Infections in Primary Immunodeficiency Disorders
Mohamad Koubeissi George Washington University Low Frequency Stimulation in Epilepsy
M. Chiara Manzini George Washington University Determining how disorders of cell-extracellular matrix interaction disrupt brain development
Gustavo Nino Children's National Molecular, Clinical and Imaging Biomarkers of Severity of Viral Respiratory Illness in Children
Brian Reilly Children's National A New Surgical Approach to Otitis Media: Dissolvable On Demand Tympanostomy Tubes
Yin Wang Children's National Targeting Early T-cell precursor Acute Lymphoblastic leukemia with Hypoxia inducible factor 1α

CSR Voucher Award Recipients

Hema Dave Children's National Correlation of P450 liver enzyme CYP2C19 with azole metabolism
Victoria Gomez-Lobo Children's National Disorders of Sexual Development-Translational Research Network
Joshua Kanter & Nefthi Sandeep Children's National A molecular assay of angiogenesis in cyanotic heart disease patients with aortopulmonary collateral vessels
Gustavo Nino Children's National Maturational Changes in Airway Response to Viral Infections
James Robinson George Washington University Use of Intravenous Tranexamic Acid During Myomectomy: A Randomized Double-Blind Placebo Controlled Trial
Nora Stinley Children's National Feasibility and Outcomes of Complementary and Alternative Pain Management 
Adeline Vanderver Children's National New Diagnostic Approaches in Leukodystrophy
Christopher Vaughan Children's National Mild Traumatic Brain Injury/Concussion Biorepository 

DEB Supplemental Voucher Award Recipients

Peter Dean & Jonathan Kaltman Children's National Sports Participation & Quality of Life in Adolescents and Young Adults with Congenital Heart Disease (SQUAD Study)

ISS, Innovation Award Recipients

Michele Mietus-Snyder Children's National IDEAL Friends Mobile or Web App
Catheeja Ismail George Washington University Sarcopenia screening: development of a feedback-augmented, portable, ultrasound device
Eleanor Mackey Children's National FLIP IT! Providing Teens with Tools for Lifetime Weight Management
Sheela Stuart Children's National THIC (Thickened-liquid Calculator)
Edward Wong Children's National Development of a novel medical device for extracorporeal treatment of hyperbilirubinemia

ISS, Translational Technology Voucher Award Recipients

Anne Chiaramello George Washington University Pharmaco-epigenetic manipulation of mitochondrial homeostasis: therapeutic implications for the pediatric mitochondrial neurodegenerative disease MELAS
Sebahattin Cirak Children's National Identification of disease genes in exome-negative CMD patients using RNAseq
Joseph Devaney Children's National Regulation of Exercise Response by the Fat Mass and Obesity-Associated (FTO) Gene
Svetlana Ghimbovschi Children's National Integrative Systems Biology approach in patients with Uterus Leiomyoma
Yetrib Hathout Children's National Development of surrogate biomarkers to monitor disease progression and response to treatment in Duchenne muscular dystrophy
Hiroki Morizono Children's National Gene therapy for urea cycle disorders: Pharmacologic augmentation of gene therapy with N-carbamylglutamate
Javad Nazarian Children's National Molecular Heterogeneity of Pediatric Brain Tumors
Terence Partridge Children's National Tracing the proteomic changes that accord with onset of disease in dysferlin-deficient skeletal muscle
Brian Rood Children's National Sub-Group Specific Medulloblastoma Protein Biomarkers
Mary Rose Children's National A Quantitative Proteomics Approach towards identifying the pathogenesis of CF lung disease
Mariam Said Children's National Evaluation of Ro52/TRIM21 polymorphism as a predictor for the development of necrotizing enterocolitis (NEC)
Xiaofang Wu Children's National Identification of the Genes/Pathways that Induce Submucosal Gland Hyperplasia/Hypertrophy following exposure to Tobacco Smoke 

2013
CSR Voucher Award Recipients

Robert Avery Children's National Neuro-ophthalmology Biobank and Data Registry
Kimberly Chapman Children's National Clinical and Basic Investigations of Methylmalonic Acidemia and Related Disorders
Susan Knoblach Children's National Biomarkers of Traumatic Brain Injury in Children and Adolescents
Adeline Vanderver Children's National New Diagnostic Approaches in Leukodystrophy

ISS, Technology Transfer Voucher Award Recipients

Brian Kirmse Children's National The genetics of metabolism in HIV exposed and infected children 
Judy Liu Children's National Transcriptome Profiling of Focal Epilepsy
Dominic Raj George Washington University MicroRNA as biomarker in glomerular disease

KL2 (Cycle V)

Emily Meier Children's National Reticulocyte as Risk Marker: Targeted Therapy for Infants with Sickle Cell Anemia
Nickie Niforatos Children's National Brain Development in the Fetus with Growth Restriction

Pilot Research Awards for Faculties of Children’s National and George Washington University (Cycle XII)

Monika Goyal Children's National Universal Sexually Transmitted Infection Screening in the Emergency Department:  A Pilot Study to assess Acceptability, Feasibility, and Prevalence
Steven Hardy Children's National Feasibility and efficacy of a home-based, computerized cognitive training program in pediatric sickle cell disease
Kazue Hashimoto-Torii Children's National Mechanisms generating cellular heterogeneity of stress response in the brain in fetuses exposed to environmental stresses
Richard Levy Children's National Developing a novel therapy for brainstem gliomas
Matthew Oetgen Children's National Development of novel non-invasive growth plate ablation treatment for children with limb-length discrepancy using MR-guided high-intensity focused ultrasound 
Elizabeth Wells Children's National Assessment of Dissociative Steroids as Dexamethasone Substitute for Pediatric Diffuse Intrinsic Pontine Glioma

Collaborative Research Grants for Children’s National, George Washington University, and Virginia Tech Faculty (Cycle XI)

Josep Bassaganya-Riera, Raquel Hontecillas, Roberta DeBiasi & David Diemert VT/VT/Children's National/GW Modeling Host Responses to Clinical Influenza Virus Clinical Isolates
Harry Dorn & Anthony Sandler VT/Children's National Antibody-Conjugated Endohedral Metallofullerene B7-H3 and IL-13 Nanoparticles for Targeted Neuroblastoma Diagnostic and Therapeutic Applications
Anelia Horvath, David Mittelman, & Raja Mazumder GW/VT/GW Novel Bioinformatics Tools for Alignment of Genomic & Transcriptomic NGS Data
Enusha Karunasena, Harold Garner & Brian Rood VT/VT/Children's National Identifying Medulloblastoma specific DNA Microsatellite Variance-Associated Targets to Create High Affinity Peptide-Based Ligands as Molecular Diagnostic Tools
Judy Liu & Alexei Morozov Children's National/VT Cellular and Molecular Basis of Focal Refractory Epilepsies
Lissett Bickford, An Massaro, Karun Sharma, Raj Shekhar, & Abby Whittington VT/Children's National/Children's National/Children's National/VT Novel Polymer Composites For In Situ Visualization of Peripherally-Inserted Central Catheters
Michael Fox & Jason Triplett VT/Children's National Mechanisms of class-specific targeting and topographic map formation in the visual system

GW/MFA Research Awards for Mentored Collaborative Pilots (Cycle X)

Harry Gill George Washington University ApoL1 Variants as a Tool to Predict Chronic Kidney Disease
Adrienne Hancock George Washington University Physiology and Health of the Aging Male-to-Female Transgender Voice
Chunlei Liang George Washington University High-fidelity Modeling and Simulation of Hemodynamic Effect of Peripheral Arterial Stenoses
Ali Ramezani George Washington University Prebiotics, Gut Microbiota, and Endotoxmia in ESRD Patients 
Lijie Zhang George Washington University Integrating Nanomaterials and 3D Printing for Personalized Osteochondral Repair

2012
Research Awards for Pilot Studies that Promote Integration of Clinical and Research Efforts (Cycle IX)

Robert Avery Children's National Immunologic And Genetic Biomarkers Of Ocular Myasthenia Gravis In Children
Ivor Horn Children's National Improving Asthma Control through mHealth-Based Home Monitoring
Susan Knoblach Children's National  Evaluation of biomarkers of mild traumatic brain injury in adolescents
Dinesh Pillai Children's National Obesity In Asthma: Adipocyte Exosomes Mediates Tgfb Signaling In Airway Epithelium
Hans Pohl Children's National Congenital Obstructive Uropathy Biomarkers Study (CUBS)
Zena Quezado Children's National Determination of Pain Sensitivity in Sickle Cell Disease Patients

CTSI-CN Translational Research Intramural Pilot Grant Program (Cycle VIII)

Matthew Colonnese George Washington University Electrical Signatures of Disease Onset in a Mouse Model for Fragile X Syndrome  
Joshua Corbin Children's National Correction of amygdala-based defects in the animal model of Fragile X Syndrome  
Aisha Liferidge George Washington University ED Patient Triage to Primary Care and Medical Home Utilization and Cost Analysis  
Judy Liu Children's National Unraveling molecular substrates underlying focal refractory epilepsies  
Larissa May George Washington University Barriers and Facilitators to Antimicrobial Stewardship for UTI in the ED Setting  
Kabir Yadav George Washington University Improved Understanding of Trauma Resuscitations to Implement Decision Support Abstract (.pdf)

KL2 (Cycle IV)

Andrea Beaton Children's National Developing a Pathway to Diagnosing Early Rheumatic Heart Disease Abstract (.pdf)
Elizabeth Carter Children's National Relating Documentation Practices to Clinical Workflow in Pediatric Trauma Resuscitation  

Exploratory/Developmental Research Awards (Cycle VII) 

Robert Freishtat Children's National Epithelial Mitotic Dyssynchrony in Fibrotic Disease

Research Awards for Pilot Feasibility Studies/Development of Methodologies/Development of New Research Technology (Cycle VI)

Jean Gutierrez George Washington University Identifying African Americans at Risk for CKD based on Genotype and Urine Markers Abstract (.pdf)
Holly Meany Children's National Phase 1 Dose Escalation Study of Sorafenib and Irinotecan Abstract (.pdf)
Lillian Su Children's National Beyond Leadership: Creating High Performance Medical Teams  

Pilot Awards for Projects in HIV/AIDS and Mental Health, Substance Use, and Behavioral Science (Cycle V)

Zhihuan Huang Georgetown University Drug use and their associations with HIV risks among female streetwalkers and their clients in Shanghai, ChinaHIV-infected older adults: a pilot study using fMRI among a high risk, community-based sample in DC
Ricardo LaGrange Children's National SmAART: A Novel mHealth Approach to Promote HIV Management with Substance Abusing Adolescents
Manya Mangus George Washington University HIV-associated neurocognitive disorders and cognitive control among HIV-infected older adults: a pilot study using fMRI among a high risk, community-based sample in DC

Children's National Support of Existing and Ongoing Clinical and Translational Research (Cycle IV)

Laurie Conklin Children's National Biomarker Discovery Utilizing MicroRNA (miRNA), Genomics, and Proteomics for Detection of Disease Activity and Response to Medications in Pediatric Inflammatory Bowel Disease (IBD)  
Kristina Hardy Children's National Computerized Cognitive Training with Preschool-aged Cancer Survivors Abstract (.pdf)
Molly Huntsman Children's National The origin of intrinsic plasticity in epileptogenesis  
Anitha John Children's National Characterization of Hepatic Dysfunction in Patients following the Fontan Operation Abstract (.pdf)
Catherine Limperopolous Children's National Quantification of Placental Structure and Function using Advanced MRI Techniques  
Jeffrey Moak Children's National Non-pharmacologic control of post-operative junctional ectopic tachycardia using AV nodal fat pad stimulation, feasibility study using an animal model.  
Rachel Moon Children's National Cultural Differences in Bed sharing Contribute to Infant Mortality Disparities  
Javad Nazarian Children's National Murine Model of Pediatric Brainstem Glioma Abstract (.pdf)
Mathew Sharron Children's National Use of Anti-Platelet Compounds to Reduce Multiple Organ Dysfunction in Sepsis  
Randi Streisand Children's National Supplement to Prevention of Disease Care Behaviors in Early Adolescents with T1 Diabetes Abstract (.pdf)
Zohreh Tatari-Calderone Children's National A Genomic Approach to Characterize Premature Infants at Risk for Developing Necrotizing Enterocolitis.  
Adeline Vanderver Children's National Molecular Mechanisms of Vanishing White Matter disease  
Irene Zohn Children's National The role of p38IP in axial skeleton defects  

2011
KL2 (Cycle III)

Larissa May George Washington University Antimicrobial Stewardship through MRSA Diagnosis in ED Patients with Abscesses Abstract(.pdf)
Qing Pan George Washington University Genetic Disparities Associated with Nephropathy, Retinopathy and Neuropathy in Type 1 Diabetes Patients Abstract (.pdf)

Pilot Projects (Cycle III)

Amanda Castel George Washington University Formative Research to Assess the Acceptability and Uptake of Pre-Exposure Prophylaxis (PrEP) with Antiretrovirals for HIV Prevention among Persons at High- Risk for HIV  
Michael Compton George Washington University A Community-Engaged Pilot Project to Prepare for Larger-Scale Anti-Stigma Schizophrenia Research  
Ivor Horn Children's National Piloting Mobile Technology to Enhance Parent Provider Communication and Improve Asthma Care  
Katherine Kelly Children's National Partnership for Academic Support and Success: PASS Abstract (.pdf)
Rachel Moon Children's National Acceptability of Educational Videos Delivered via an Electronic Patient Portal  
Earl Parrish George Washington University Formative Research to Develop a Systematic Approach for Sentiment Analysis as a Community Engagement Tool for Translation of Clinical Research and Public Health Interventions Abstract (.pdf)

Pilot Projects (Cycle II)

Ali Ramezani George Washington University Anti-HIV-1 Erythrocyte Viral Trap
Marc Siegel George Washington University Genomic Analysis of Respiratory Pathogens
Xiaofang Wu Children's National In vitro Models of Glandular Hyperplasia from Basal Cells in Pediatric Chronic Rhinosinusitis
Irene Zohn Children's National Identification of modifiers of iron deficiency induced neural tube defects

KL2 (Cycle II)

Brian Kirmse Children's National The Effects of Antiretroviral Therapy on Energy Metabolism in Children

2010
Pilot Projects (Cycle I)

Anamaris Colberg-Poley Children's National Alteration of neural precursor cell functions by human cytomegalovirus Abstract (.pdf)
Robert Freishtat Children's National Dyssynchronous Mitosis and Inflammation in Asthmatic Epithelium Abstract (.pdf)
Yetrib Hathou Children's National HTRA1 as a new target for treatment of muscular dystrophies  
Monica Hubal Children's National Genetic influences on depot-specific adipose tissue remodeling with obesity  
Lauren Kenworthy Children's National Parsing Genetic Heterogeneity in Autism with Continuous Flexibility Measures Abstract (.pdf)
Catherine Klein Children's National Electronic Intervention to Improve Health Behaviors in African American College Students (EI-AACS) Abstract (.pdf)
Andrew Meltzer George Washington University H. pylori testing for patients with non-specific abdominal pain in the Emergency Department Abstract (.pdf)
Javad Nazarian Children's National Clinical and Translational Approaches for Understanding Pediatric Brian Tumors Abstract (.pdf)
Travis O'Brien George Washington University Genetic Factors Associated with Ovarian Hyperstimulation Syndrome Abstract (.pdf)
Diego Preciado Children's National Biological Repair of Airway Defects Using BMP-2 in Extracellular Matrix Gel Abstract (.pdf)
Irene Riz George Washington University Apoptotic Role of NfkB in T-All Therapeutic Response Abstract (.pdf)
Xiaoyan Song Children's National Clostridium difficile Infections in Children: Epidemiology, Treatment, and Outcomes Abstract (.pdf)
Amita Vyas George Washington University Prevention of Type 2 Diabetes Among South Asian American Families Abstract (.pdf)
Zuyi Wang Children's National Computational systems biology to develop a testable model of glucocorticoid action in asthma. Abstract (.pdf)
Lijie Zhang George Washington University Biologically Inspired 3D Nanostructured Bone Substitutes for Children Bone Repair and Regeneration Abstract (.pdf)

Novel Clinical and Translational Methodologies (Cycle I)

Kristy Brown Children's National Method Development for A Antisense Oligonucleotide Tissue Detection Assay Abstract (.pdf)
Michael Keidar George Washington University Cold plasma cancer therapy Abstract (.pdf)
Zhenyu Li George Washington University A Miniaturized Biosensor for Fast Screening of Infant Patients’ Serostatus or Genotype Using Small Volume (<50uL) Heel Prick Whole Blood Samples Abstract (.pdf)
Christopher Spurney Children's National Use of plethysmography as a novel outcome measure in mouse models of congenital muscular dystrophy Abstract (.pdf)

KL2 (Cycle I)

Maureen Monaghan Children's National Predictors of Health Outcomes in Emerging Adults with T1 Diabetes Abstract (.pdf)
Kabir Yadav George Washington University Better, Stronger, Faster: Translating Biomedical Informatics Tools to Accelerate Comparative Effectiveness Research Abstract (.pdf)