CTSI-CN Awardees

2014

CSR Voucher Award Recipients

Joshua KanterChildren's NationalA molecular assay of angiogenesis in cyanotic heart disease patients with aortopulmonary collateral vessels
Gustavo NinoChildren's NationalMaturational Changes in Airway Response to Viral Infections

ISS, Innovation Award Recipients

Floortje Blindenbach-DriessenChildren's NationalIDEAL Friends Mobile or Web App
Catheeja IsmailGeorge Washington UniversitySarcopenia screening: development of a feedback-augmented, portable, ultrasound device
Eleanor MackeyChildren's NationalFLIP IT! Providing Teens with Tools for Lifetime Weight Management
Sheela StuartChildren's NationalTHIC (Thickened-liquid Calculator)
Edward WongChildren's NationalDevelopment of a novel medical device for extracorporeal treatment of hyperbilirubinemia

ISS, Translational Technology Voucher Award Recipients

Anne ChiaramelloGeorge Washington UniversityPharmaco-epigenetic manipulation of mitochondrial homeostasis: therapeutic implications for the pediatric mitochondrial neurodegenerative disease MELAS
Sebahattin CirakChildren's NationalIdentification of disease genes in exome-negative CMD patients using RNAseq
Joseph DevaneyChildren's NationalRegulation of Exercise Response by the Fat Mass and Obesity-Associated (FTO) Gene
Svetlana GhimbovschiChildren's NationalIntegrative Systems Biology approach in patients with Uterus Leiomyoma
Yetrib HathoutChildren's NationalDevelopment of surrogate biomarkers to monitor disease progression and response to treatment in Duchenne muscular dystrophy
Hiroki MorizonoChildren's NationalGene therapy for urea cycle disorders: Pharmacologic augmentation of gene therapy with N-carbamylglutamate
Javad NazarianChildren's NationalMolecular Heterogeneity of Pediatric Brain Tumors
Terence PartridgeChildren's NationalTracing the proteomic changes that accord with onset of disease in dysferlin-deficient skeletal muscle
Brian RoodChildren's NationalSub-Group Specific Medulloblastoma Protein Biomarkers
Mary RoseChildren's NationalA Quantitative Proteomics Approach towards identifying the pathogenesis of CF lung disease
Mariam SaidChildren's NationalEvaluation of Ro52/TRIM21 polymorphism as a predictor for the development of necrotizing enterocolitis (NEC)
Xiaofang WuChildren's NationalIdentification of the Genes/Pathways that Induce Submucosal Gland Hyperplasia/Hypertrophy following exposure to Tobacco Smoke 

2013
CSR Voucher Award Recipients

Robert AveryChildren's NationalNeuro-ophthalmology Biobank and Data Registry
Kimberly ChapmanChildren's NationalClinical and Basic Investigations of Methylmalonic Acidemia and Related Disorders
Susan KnoblachChildren's NationalBiomarkers of Traumatic Brain Injury in Children and Adolescents
Adeline VanderverChildren's NationalNew Diagnostic Approaches in Leukodystrophy

ISS, Technology Transfer Voucher Award Recipients

Brian KirmseChildren's NationalThe genetics of metabolism in HIV exposed and infected children 
Judy LiuChildren's NationalTranscriptome Profiling of Focal Epilepsy
Dominic RajGeorge Washington UniversityMicroRNA as biomarker in glomerular disease

KL2 (Cycle V)

Emily MeierChildren's NationalReticulocyte as Risk Marker: Targeted Therapy for Infants with Sickle Cell Anemia
Nickie NiforatosChildren's NationalBrain Development in the Fetus with Growth Restriction

Pilot Research Awards for the Faculties of Children’s National and George Washington University (Cycle XII)

Monika GoyalChildren's NationalUniversal Sexually Transmitted Infection Screening in the Emergency Department:  A Pilot Study to assess Acceptability, Feasibility, and Prevalence
Steven HardyChildren's NationalFeasibility and efficacy of a home-based, computerized cognitive training program in pediatric sickle cell disease
Kazue Hashimoto-ToriiChildren's NationalMechanisms generating cellular heterogeneity of stress response in the brain in fetuses exposed to environmental stresses
Richard LevyChildren's NationalDeveloping a novel therapy for brainstem gliomas
Matthew OetgenChildren's NationalDevelopment of novel non-invasive growth plate ablation treatment for children with limb-length discrepancy using MR-guided high-intensity focused ultrasound 
Elizabeth WellsChildren's NationalAssessment of Dissociative Steroids as Dexamethasone Substitute for Pediatric Diffuse Intrinsic Pontine Glioma

Collaborative Research Grants for Children’s National, George Washington University, and Virginia Tech Faculty (Cycle XI)

Josep Bassaganya-Riera, Raquel Hontecillas, Roberta DeBiasi and David DiemertVT/VT/Children's National/GWModeling Host Responses to Clinical Influenza Virus Clinical Isolates
Harry Dorn and Anthony SandlerVT/Children's NationalAntibody-Conjugated Endohedral Metallofullerene B7-H3 and IL-13 Nanoparticles for Targeted Neuroblastoma Diagnostic and Therapeutic Applications
Anelia Horvath, David Mittelman, and Raja MazumderGW/VT/GWNovel Bioinformatics Tools for Alignment of Genomic & Transcriptomic NGS Data
Enusha Karunasena, Harold Garner and Brian RoodVT/VT/Children's NationalIdentifying Medulloblastoma specific DNA Microsatellite Variance-Associated Targets to Create High Affinity Peptide-Based Ligands as Molecular Diagnostic Tools
Judy Liu and Alexei MorozovChildren's National/VTCellular and Molecular Basis of Focal Refractory Epilepsies
Lissett Bickford, An Massaro, Karun Sharma, Raj Shekhar, and Abby WhittingtonVT/Children's National/Children's National/Children's National/VTNovel Polymer Composites For In Situ Visualization of Peripherally-Inserted Central Catheters
Michael Fox and Jason TriplettVT/Children's NationalMechanisms of class-specific targeting and topographic map formation in the visual system

GW/MFA Research Awards for Mentored Collaborative Pilots (Cycle X)

Harry GillGeorge Washington UniversityApoL1 Variants as a Tool to Predict Chronic Kidney Disease
Adrienne HancockGeorge Washington UniversityPhysiology and Health of the Aging Male-to-Female Transgender Voice
Chunlei LiangGeorge Washington UniversityHigh-fidelity Modeling and Simulation of Hemodynamic Effect of Peripheral Arterial Stenoses
Ali RamezaniGeorge Washington UniversityPrebiotics, Gut Microbiota, and Endotoxmia in ESRD Patients 
Lijie ZhangGeorge Washington UniversityIntegrating Nanomaterials and 3D Printing for Personalized Osteochondral Repair

2012
Research Awards for Pilot Studies that Promote Integration of Clinical and Research Efforts (Cycle IX)

Robert AveryChildren's NationalImmunologic And Genetic Biomarkers Of Ocular Myasthenia Gravis In Children
Ivor HornChildren's NationalImproving Asthma Control through mHealth-Based Home Monitoring
Susan KnoblachChildren's National Evaluation of biomarkers of mild traumatic brain injury in adolescents
Dinesh PillaiChildren's NationalObesity In Asthma: Adipocyte Exosomes Mediates Tgfb Signaling In Airway Epithelium
Hans PohlChildren's NationalCongenital Obstructive Uropathy Biomarkers Study (CUBS)
Zena QuezadoChildren's NationalDetermination of Pain Sensitivity in Sickle Cell Disease Patients

CTSI-CN Translational Research Intramural Pilot Grant Program (Cycle VIII)

Matthew ColonneseGeorge Washington UniversityElectrical Signatures of Disease Onset in a Mouse Model for Fragile X Syndrome 
Joshua CorbinChildren's NationalCorrection of amygdala-based defects in the animal model of Fragile X Syndrome 
Aisha LiferidgeGeorge Washington UniversityED Patient Triage to Primary Care and Medical Home Utilization and Cost Analysis 
Judy LiuChildren's NationalUnraveling molecular substrates underlying focal refractory epilepsies 
Larissa MayGeorge Washington UniversityBarriers and Facilitators to Antimicrobial Stewardship for UTI in the ED Setting 
Kabir YadavGeorge Washington UniversityImproved Understanding of Trauma Resuscitations to Implement Decision SupportAbstract (.pdf)

KL2 (Cycle IV)

Andrea BeatonChildren's NationalDeveloping a Pathway to Diagnosing Early Rheumatic Heart DiseaseAbstract (.pdf)
Elizabeth CarterChildren's NationalRelating Documentation Practices to Clinical Workflow in Pediatric Trauma Resuscitation 

Exploratory/Developmental Research Awards (Cycle VII) 

Robert FreishtatChildren's NationalEpithelial Mitotic Dyssynchrony in Fibrotic Disease

Research Awards for Pilot Feasibility Studies/Development of Methodologies/Development of New Research Technology (Cycle VI)

Jean GutierrezGeorge Washington UniversityIdentifying African Americans at Risk for CKD based on Genotype and Urine MarkersAbstract (.pdf)
Holly MeanyChildren's NationalPhase 1 Dose Escalation Study of Sorafenib and IrinotecanAbstract (.pdf)
Lillian SuChildren's NationalBeyond Leadership: Creating High Performance Medical Teams 

Pilot Awards for Projects in HIV/AIDS and Mental Health, Substance Use, and Behavioral Science (Cycle V)

Zhihuan HuangGeorgetown UniversityDrug use and their associations with HIV risks among female streetwalkers and their clients in Shanghai, ChinaHIV-infected older adults: a pilot study using fMRI among a high risk, community-based sample in DC
Ricardo LaGrangeChildren's NationalSmAART: A Novel mHealth Approach to Promote HIV Management with Substance Abusing Adolescents
Manya MangusGeorge Washington UniversityHIV-associated neurocognitive disorders and cognitive control among HIV-infected older adults: a pilot study using fMRI among a high risk, community-based sample in DC

Children's National Support of Existing and Ongoing Clinical and Translational Research (Cycle IV)

Laurie ConklinChildren's NationalBiomarker Discovery Utilizing MicroRNA (miRNA), Genomics, and Proteomics for Detection of Disease Activity and Response to Medications in Pediatric Inflammatory Bowel Disease (IBD) 
Kristina HardyChildren's NationalComputerized Cognitive Training with Preschool-aged Cancer SurvivorsAbstract (.pdf)
Molly HuntsmanChildren's NationalThe origin of intrinsic plasticity in epileptogenesis 
Anitha JohnChildren's NationalCharacterization of Hepatic Dysfunction in Patients following the Fontan OperationAbstract (.pdf)
Catherine LimperopolousChildren's NationalQuantification of Placental Structure and Function using Advanced MRI Techniques 
Jeffrey MoakChildren's NationalNon-pharmacologic control of post-operative junctional ectopic tachycardia using AV nodal fat pad stimulation, feasibility study using an animal model. 
Rachel MoonChildren's NationalCultural Differences in Bed sharing Contribute to Infant Mortality Disparities 
Javad NazarianChildren's NationalMurine Model of Pediatric Brainstem GliomaAbstract (.pdf)
Mathew SharronChildren's NationalUse of Anti-Platelet Compounds to Reduce Multiple Organ Dysfunction in Sepsis 
Randi StreisandChildren's NationalSupplement to Prevention of Disease Care Behaviors in Early Adolescents with T1 DiabetesAbstract (.pdf)
Zohreh Tatari-CalderoneChildren's NationalA Genomic Approach to Characterize Premature Infants at Risk for Developing Necrotizing Enterocolitis. 
Adeline VanderverChildren's NationalMolecular Mechanisms of Vanishing White Matter disease 
Irene ZohnChildren's NationalThe role of p38IP in axial skeleton defects 

2011
KL2 (Cycle III)

Larissa MayGeorge Washington UniversityAntimicrobial Stewardship through MRSA Diagnosis in ED Patients with AbscessesAbstract(.pdf)
Qing PanGeorge Washington UniversityGenetic Disparities Associated with Nephropathy, Retinopathy and Neuropathy in Type 1 Diabetes PatientsAbstract (.pdf)

Pilot Projects (Cycle III)

Amanda CastelGeorge Washington UniversityFormative Research to Assess the Acceptability and Uptake of Pre-Exposure Prophylaxis (PrEP) with Antiretrovirals for HIV Prevention among Persons at High- Risk for HIV 
Michael ComptonGeorge Washington UniversityA Community-Engaged Pilot Project to Prepare for Larger-Scale Anti-Stigma Schizophrenia Research 
Ivor HornChildren's NationalPiloting Mobile Technology to Enhance Parent Provider Communication and Improve Asthma Care 
Katherine KellyChildren's NationalPartnership for Academic Support and Success: PASSAbstract (.pdf)
Rachel MoonChildren's NationalAcceptability of Educational Videos Delivered via an Electronic Patient Portal 
Earl ParrishGeorge Washington UniversityFormative Research to Develop a Systematic Approach for Sentiment Analysis as a Community Engagement Tool for Translation of Clinical Research and Public Health InterventionsAbstract (.pdf)

Pilot Projects (Cycle II)

Ali RamezaniGeorge Washington UniversityAnti-HIV-1 Erythrocyte Viral Trap
Marc SiegelGeorge Washington UniversityGenomic Analysis of Respiratory Pathogens
Xiaofang WuChildren's NationalIn vitro Models of Glandular Hyperplasia from Basal Cells in Pediatric Chronic Rhinosinusitis
Irene ZohnChildren's NationalIdentification of modifiers of iron deficiency induced neural tube defects

KL2 (Cycle II)

Brian KirmseChildren's NationalThe Effects of Antiretroviral Therapy on Energy Metabolism in Children

2010
Pilot Projects (Cycle I)

Anamaris Colberg-PoleyChildren's NationalAlteration of neural precursor cell functions by human cytomegalovirusAbstract (.pdf)
Robert FreishtatChildren's NationalDyssynchronous Mitosis and Inflammation in Asthmatic EpitheliumAbstract (.pdf)
Yetrib HathouChildren's NationalHTRA1 as a new target for treatment of muscular dystrophies 
Monica HubalChildren's NationalGenetic influences on depot-specific adipose tissue remodeling with obesity 
Lauren KenworthyChildren's NationalParsing Genetic Heterogeneity in Autism with Continuous Flexibility MeasuresAbstract (.pdf)
Catherine KleinChildren's NationalElectronic Intervention to Improve Health Behaviors in African American College Students (EI-AACS)Abstract (.pdf)
Andrew MeltzerGeorge Washington UniversityH. pylori testing for patients with non-specific abdominal pain in the Emergency DepartmentAbstract (.pdf)
Javad NazarianChildren's NationalClinical and Translational Approaches for Understanding Pediatric Brian TumorsAbstract (.pdf)
Travis O'BrienGeorge Washington UniversityGenetic Factors Associated with Ovarian Hyperstimulation SyndromeAbstract (.pdf)
Diego PreciadoChildren's NationalBiological Repair of Airway Defects Using BMP-2 in Extracellular Matrix GelAbstract (.pdf)
Irene RizGeorge Washington UniversityApoptotic Role of NfkB in T-All Therapeutic ResponseAbstract (.pdf)
Xiaoyan SongChildren's NationalClostridium difficile Infections in Children: Epidemiology, Treatment, and OutcomesAbstract (.pdf)
Amita VyasGeorge Washington UniversityPrevention of Type 2 Diabetes Among South Asian American FamiliesAbstract (.pdf)
Zuyi WangChildren's NationalComputational systems biology to develop a testable model of glucocorticoid action in asthma.Abstract (.pdf)
Lijie ZhangGeorge Washington UniversityBiologically Inspired 3D Nanostructured Bone Substitutes for Children Bone Repair and RegenerationAbstract (.pdf)

Novel Clinical and Translational Methodologies (Cycle I)

Kristy BrownChildren's NationalMethod Development for A Antisense Oligonucleotide Tissue Detection AssayAbstract (.pdf)
Michael KeidarGeorge Washington UniversityCold plasma cancer therapyAbstract (.pdf)
Zhenyu LiGeorge Washington UniversityA Miniaturized Biosensor for Fast Screening of Infant Patients’ Serostatus or Genotype Using Small Volume (<50uL) Heel Prick Whole Blood SamplesAbstract (.pdf)
Christopher SpurneyChildren's NationalUse of plethysmography as a novel outcome measure in mouse models of congenital muscular dystrophyAbstract (.pdf)

KL2 (Cycle I)

Maureen MonaghanChildren's NationalPredictors of Health Outcomes in Emerging Adults with T1 DiabetesAbstract (.pdf)
Kabir YadavGeorge Washington UniversityBetter, Stronger, Faster: Translating Biomedical Informatics Tools to Accelerate Comparative Effectiveness ResearchAbstract (.pdf)