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Awarded Projects

2017

KL2 Career Development Award (GY02)

Name Institution Project Title
Homa Ahmadzia The George Washington University Prevention of postpartum hemorrhage: identifying women at risk and PK/PD of Tranexamic acid
John Strang Children's National Health System Anthropometric and Neural Correlates in Co-Occuring Autism and Gender Dysphoria

CTSI-CN v2.0 GY01 GW Winter Voucher Award Program

Name Institution Project Title
Marcos Perez-Losada
The George Washington University
Transmission of pathogens and antimicrobial resistance genes by fecal transplant in children
Ali Ramezani
The George Washington University
Investigation of plasma and urine miRNA profiles associated with progression of CKD in teh CRIC cohort
Ian Toma
The George Washington University
Immune response to Bacillus Calmette-Guerin (BCG) vaccination in neonates born to HIV infected pregnant women
Amanda Visek
The George Washington University
Secondary analysis of the FUN MAPS to sustain sport-based physical activities

CTSI-CN v2.0 GY01 GW Winter Voucher Award Program

Name
Institution
Project Title
Andrea Beaton
Children's National Health System
Understanding the Natural History of Latent RHD in Ugandan Youth
Kazue Hashimoto-Torii
Children's National Health System
Consulting for Preparation of NIH/NIAAA STTR Application
Lana Ismail
Children's National Health System
Evaluating echocardiography use forr murmurs in the newborn nursery
Lauren Kenworthy
Children's National Health System
Community-Based Intervention for Children with ADHD and ASD
Tessie October
Children's National Health System
Enhancing Physician Communication Skills
Shilpa Patel
Children's National Health System
StethAid for Lungs: A mobile app for recording lungs sounds  
Subechhya Pradhan
Children's National Health System
Optimizing Imaging Techniques for Fetal and Neonatal MRI
Mary Revenis
Children's National Health System
Inflammatory and Brain Injury Biomarkers of Injury in Animal Model of Apnea of Prematurity
Christopher Spurney
Children's National Health System
Longitudinal functional outcomes with a focus of cardiac health in boys and adolescents with muscular dystrophy
Laura Tosi
Children's National Health System
Validation of genome association studies

KL2 Career Development Award (GY01)

Name
Institution
Project Title
Aileen Chang
George Washignton University
Zika-induced Guillain-Barre Syndrome: Elucidating the role of antibodies
Sarah Mulkey
Children's National Health System
Dysautonomia of prematurity and neurologic outcome

 

2016

CTSI-CN v2.0 GY01 Fall Voucher Award Program

Name
Institution
Project Title
Binny Chokshi Children's National Health System Assessment of Feedback delivered by Faculty During Observed Structured Clinical Examination
Uriyoan Colon-Ramos The George Washington University Understanding the social drivers for health: Mechanisms between family environment and diet quality among
Latino adults and youth
Nikki Posnack Childen's National Health System Pediatric risk assessment of medical device polymers

CTSI-CN Voucher Award Program

Name Institution Project Title
Youssef Kousa Children's National Health System Identification of host genetic risk factors in Congenital Zika Syndrome

CTSI-CN v2.0 GY01 2016-2017 Pilot Award

Name
Institution
Project Title
Sudeepta K. Basu
Children's National Health System
In vivo quantification of gama-aminobutyric acid in the developing brain of preterm infants
M. Chiara Manzini
The George Washington University
Defining the molecular mechanisms of sex differences in neurodevelopmental disorders
Ashley Darcy-Mahoney
The George Washington University
Characterizing Sensory Hypersensitivities in young toddlers with Autism
Nikki Gillum Posnack
Children's National Health System
Human Induced Pluripotent Stem Cell Models for Pediatric Risk Assessment
Allison C. Meni Sylvetsky
The George Washington University
Low-calorie sweeteners induce metabolic dysregulation via alterations in adipose signaling
Maureen Monaghan
Children's National Health System
Improving Health Communication in Adolescents and Young Adults with Type 1 Diabetes
Marcos Perez-Losada
The George Washington University
Connect to Conquer: Integrating Clinical, Genomic and Microbial Information to Better Characterize Pediatric Asthma
John M. Schreiber
Children's National Health System
Use of Echocardiography to Assess Subclinical Myocardial Damage in Children with Refractory Epilepsy or Status Epilepticus
Yin Wang
Children's National Health System
Identification of a Druggable Target for MYC Inhibition for Treatment of Group 3 Medulloblastoma

The Connor Family Innovation Award 

Name
Institution 
Project Title
Justin Burton
Children's National Health System
A novel mechanical hippotherapy training platformsimulator for children with neurological/musculoskeletal disabilities

Clinical Studies Support/Clinical Research Center Voucher Award

Name
Institution
Project Title
Kimberly Chapman
Children's National Health System
Bio-repository for cells, tissues, and DNA
Sarah Evans
Children's National Health System
Effects of tactile therapy on hand function in children with hemiplegic cerebal palsy: A feasibility study
Sharyn Malcolm
Children's National Health System
Reproductive Issues in Adolescent Females with Polycystic Ovary

Innovative Strategies and Services Voucher Award

Name
Institution
Project Title
Li-Jin Chew
Children's National Health System
Sox17-induced alterations in beta-catenin-associated proteins
Andrea Hahn
Children's National Health System
Metagenomic evaluation of the lung microbiome with antibiotic treatment in cystic fibrosis
Matthew Oetgen
Children's National Health System
Structural Health Monitoring of Spinal Growing Rods - Design and Production of Instruments
Yanxin Pei
Children's National Health System
Overcoming Therapeutic Resistance in MYC-driven Group 3 Medulloblastoma
Nikki Posnack
Children's National Health System
Cardiovascular health risks associated with phthalate exposure
Masaaki Torii
Children's National Health System
Identification of Proteins Involved with Corpus Callosum Refinement

 

2015

Pilot Research Awards for Faculties of Children’s National and George Washington University

Name
Institution
Project Title
Cynthia Dowd
The George Washington University
Targeting Malaria Through Inhibition of MEP Isoprenoid Biosynthesis
Monica Hubal
The George Washington University
Are Insulin Signaling Improvements following Bariatric Surgery Driven by Adipose-Derived Exosomal microRNA Changes
Amanda Levin
Children's National Health System
Pediatric Rapid Response Teams: Improve the Team to Improve Patient Outcomes
Javad Nazarian
Children's National Health System
Reversal of Aberrant Cancer Epigenome
Nikki Gillum Posnack
The George Washington University
Assessing cardiovascular health risks due to plasticizer exposure in chronically transfused patients
Brian Reilly
Children's National Health System
EARgraft: Improved ear drum repair using a custom 3D bioprinted graft
Zungho Wesley Zun
Children's National Health System
Non-invasive imaging of placental insufficiency using in vivo arterial spin labeled MRI

 

2014

Pilot Research Awards for Faculties of Children’s National and George Washington University (Cycle XIII)

Name
Institution
Project Title
Anne Chiaramello
George Washington University
A Novel Epigenetic and Metabolic Approach for the Pediatric Mitochondrial Disease MELAS
Niti Dham
Children's National Health System
Early Detection of Cardiac Toxicity in Childhood Cancer Survivors
Yaser Diab
Children's National Health System
High on-Aspirin Platelet Reactivity /Aspirin Resistance in Children Undergoing Fontan Palliation for Single Ventricle Physiology
Rohan Fernandes
Children's National Health System
Prussian blue nanoparticles for laser-induced photothermal therapy of neuroblastomas
Michael Keller
 
Adoptive immunotherapy for Treatment of Viral Infections in Primary Immunodeficiency Disorders
Mohamad Koubeissi
George Washington University
Low Frequency Stimulation in Epilepsy
M. Chiara Manzini
George Washington University
Determining how disorders of cell-extracellular matrix interaction disrupt brain development
Gustavo Nino
Children's National Health System
Molecular, Clinical and Imaging Biomarkers of Severity of Viral Respiratory Illness in Children
Brian Reilly
Children's National Health System
A New Surgical Approach to Otitis Media: Dissolvable On Demand Tympanostomy Tubes
Yin Wang
Children's National Health System
Targeting Early T-cell precursor Acute Lymphoblastic leukemia with Hypoxia inducible factor 1α

Clinical Studies Support/Clinical Research Center Voucher Award

Name
Institution
Project Name
Hema Dave
Children's National Health System
Correlation of P450 liver enzyme CYP2C19 with azole metabolism
Victoria Gomez-Lobo
Children's National Health System
Disorders of Sexual Development-Translational Research Network
Joshua Kanter & Nefthi Sandeep
Children's National Health System
A molecular assay of angiogenesis in cyanotic heart disease patients with aortopulmonary collateral vessels
Catherine Limperopoulos
Children's National Health System
Antecedents of Impaired Brain Development in Fetuses with Heart Disease
Gustavo Nino
Children's National Health System
Maturational Changes in Airway Response to Viral Infections
James Robinson
George Washington University
Use of Intravenous Tranexamic Acid During Myomectomy: A Randomized Double-Blind Placebo Controlled Trial
Nora Stinley
Children's National Health System
Feasibility and Outcomes of Complementary and Alternative Pain Management 
Adeline Vanderver
Children's National Health System
New Diagnostic Approaches in Leukodystrophy
Christopher Vaughan
Children's National Health System
Mild Traumatic Brain Injury/Concussion Biorepository 

ISS, Innovation Award

Name
Institution
Project Title
Michele Mietus-Snyder
Children's National Health System
IDEAL Friends Mobile or Web App
Catheeja Ismail
George Washington University
Sarcopenia screening: development of a feedback-augmented, portable, ultrasound device
Eleanor Mackey
Children's National Health System
FLIP IT! Providing Teens with Tools for Lifetime Weight Management
Sheela Stuart
Children's National Health System
THIC (Thickened-liquid Calculator)
Edward Wong
Children's National Health System
Development of a novel medical device for extracorporeal treatment of hyperbilirubinemia

ISS, Translational Technology Voucher Award

Name
Institution
Project Name
Anne Chiaramello
The George Washington University
Pharmaco-epigenetic manipulation of mitochondrial homeostasis: therapeutic implications for the pediatric mitochondrial neurodegenerative disease MELAS
Sebahattin Cirak
Children's National Health System
Identification of disease genes in exome-negative CMD patients using RNAseq
Joseph Devaney
Children's National Health System
Regulation of Exercise Response by the Fat Mass and Obesity-Associated (FTO) Gene
Svetlana Ghimbovschi
Children's National Health System
Integrative Systems Biology approach in patients with Uterus Leiomyoma
Yetrib Hathout
Children's National Health System
Development of surrogate biomarkers to monitor disease progression and response to treatment in Duchenne muscular dystrophy
Hiroki Morizono
Children's National Health System
Gene therapy for urea cycle disorders: Pharmacologic augmentation of gene therapy with N-carbamylglutamate
Javad Nazarian
Children's National Health System
Molecular Heterogeneity of Pediatric Brain Tumors
Terence Partridge
Children's National Health System
Tracing the proteomic changes that accord with onset of disease in dysferlin-deficient skeletal muscle
Brian Rood
Children's National Health System
Sub-Group Specific Medulloblastoma Protein Biomarkers
Mary Rose
Children's National Health System
A Quantitative Proteomics Approach towards identifying the pathogenesis of CF lung disease
Mariam Said
Children's National Health System
Evaluation of Ro52/TRIM21 polymorphism as a predictor for the development of necrotizing enterocolitis (NEC)
Xiaofang Wu
Children's National Health System
Identification of the Genes/Pathways that Induce Submucosal Gland Hyperplasia/Hypertrophy following exposure to Tobacco Smoke 
 

2013

Clinical Studies Support/Clinical Research Center Voucher Award

Name
Institution
Project Title
Robert Avery
Children's National Health System
Neuro-ophthalmology Biobank and Data Registry
Kimberly Chapman
Children's National Health System
Clinical and Basic Investigations of Methylmalonic Acidemia and Related Disorders
Susan Knoblach
Children's National Health System
Biomarkers of Traumatic Brain Injury in Children and Adolescents
Adeline Vanderver
Children's National Health System
New Diagnostic Approaches in Leukodystrophy

ISS, Technology Transfer Voucher Award

Name
Institution
Project Title
Brian Kirmse
Children's National Health System
The genetics of metabolism in HIV exposed and infected children 
Judy Liu
Children's National Health System
Transcriptome Profiling of Focal Epilepsy
Dominic Raj
George Washington University
MicroRNA as biomarker in glomerular disease

KL2 (Cycle V)

Name
Institution
Project Title
Emily Meier
Children's National Health System
Reticulocyte as Risk Marker: Targeted Therapy for Infants with Sickle Cell Anemia
Nickie Niforatos
Children's National Health System
Brain Development in the Fetus with Growth Restriction

Pilot Research Awards for Faculties of Children’s National and George Washington University (Cycle XII)

Name
Institution
Project Title
Monika Goyal
Children's National Health System
Universal Sexually Transmitted Infection Screening in the Emergency Department:  A Pilot Study to assess Acceptability, Feasibility, and Prevalence
Steven Hardy
Children's National Health System
Feasibility and efficacy of a home-based, computerized cognitive training program in pediatric sickle cell disease
Kazue Hashimoto-Torii
Children's National Health System
Mechanisms generating cellular heterogeneity of stress response in the brain in fetuses exposed to environmental stresses
Richard Levy
Children's National Health System
Developing a novel therapy for brainstem gliomas
Matthew Oetgen
Children's National Health System
Development of novel non-invasive growth plate ablation treatment for children with limb-length discrepancy using MR-guided high-intensity focused ultrasound 
Elizabeth Wells
Children's National Health System
Assessment of Dissociative Steroids as Dexamethasone Substitute for Pediatric Diffuse Intrinsic Pontine Glioma

Collaborative Research Grants for Children’s National, George Washington University, and Virginia Tech Faculty (Cycle XI)

Name
Institution
Project Title
Josep Bassaganya-Riera1, Raquel Hontecillas1,
Roberta DeBiasi2 & David Diemert3
1 Virginia Tech
2 Children's National Health System 
3 The George Washington University 
Modeling Host Responses to Clinical Influenza Virus Clinical Isolates
Harry Dorn1 & Anthony Sandler2
Virginia Tech
Children's National Health System 
Antibody-Conjugated Endohedral Metallofullerene B7-H3 and IL-13 Nanoparticles for Targeted Neuroblastoma Diagnostic and Therapeutic Applications
Anelia Horvath1, David Mittelman2
& Raja Mazumder1
1 The George Washington University 
2 Viriginia Tech 
Novel Bioinformatics Tools for Alignment of Genomic & Transcriptomic NGS Data
Enusha Karunasena1, Harold Garner1
& Brian Rood2
1 Virginia Tech
2 Children's National Health System 
Identifying Medulloblastoma specific DNA Microsatellite Variance-Associated Targets to Create High Affinity Peptide-Based Ligands as Molecular Diagnostic Tools
Judy Liu1 & Alexei Morozov2
1 Children's National Health System 
2 Virginia Tech 
Cellular and Molecular Basis of Focal Refractory Epilepsies
Lissett Bickford1, An Massaro2, Karun Sharma2,
Raj Shekhar2 & Abby Whittington1
1 Virginia Tech
2 Children's National Health System 
Novel Polymer Composites For In Situ Visualization of Peripherally-Inserted Central Catheters
Michael Fox1 & Jason Triplett2
1 Virginia Tech
2 Children's National Health System 
Mechanisms of class-specific targeting and topographic map formation in the visual system

 

2012

Research Awards for Pilot Studies that Promote Integration of Clinical and Research Efforts (Cycle IX)

Name
Institution
Project Title
Robert Avery
Children's National Health System
Immunologic And Genetic Biomarkers Of Ocular Myasthenia Gravis In Children
Ivor Horn
Children's National Health System
Improving Asthma Control through mHealth-Based Home Monitoring
Susan Knoblach
Children's National Health System
Evaluation of biomarkers of mild traumatic brain injury in adolescents
Dinesh Pillai
Children's National Health System
Obesity In Asthma: Adipocyte Exosomes Mediates Tgfb Signaling In Airway Epithelium
Hans Pohl
Children's National Health System
Congenital Obstructive Uropathy Biomarkers Study (CUBS)
Zena Quezado
Children's National Health System
Determination of Pain Sensitivity in Sickle Cell Disease Patients

CTSI-CN Translational Research Intramural Pilot Grant Program (Cycle VIII)

Name
Institution
Project Title
Matthew Colonnese
George Washington University
Electrical Signatures of Disease Onset in a Mouse Model for Fragile X Syndrome
Joshua Corbin
Children's National Health System
Correction of amygdala-based defects in the animal model of Fragile X Syndrome
Aisha Liferidge
George Washington University
ED Patient Triage to Primary Care and Medical Home Utilization and Cost Analysis
Judy Liu
Children's National Health System
Unraveling molecular substrates underlying focal refractory epilepsies
Larissa May
George Washington University
Barriers and Facilitators to Antimicrobial Stewardship for UTI in the ED Setting
Kabir Yadav
George Washington University
Improved Understanding of Trauma Resuscitations to Implement Decision Support

KL2 (Cycle IV)

Name
Institution
Project Title
Andrea Beaton
Children's National Health System
Developing a Pathway to Diagnosing Early Rheumatic Heart Disease
Elizabeth Carter
Children's National Health System
Relating Documentation Practices to Clinical Workflow in Pediatric Trauma Resuscitation

Exploratory/Developmental Research Awards (Cycle VII) 

Name
Institution
Project Title
Robert Freishtat
Children's National Health System
Epithelial Mitotic Dyssynchrony in Fibrotic Disease

Research Awards for Pilot Feasibility Studies/Development of Methodologies/Development of New Research Technology (Cycle VI)

Name
Institution
Project Title
Jean Gutierrez
George Washington University
Identifying African Americans at Risk for CKD based on Genotype and Urine Markers
Holly Meany
Children's National Health System
Phase 1 Dose Escalation Study of Sorafenib and Irinotecan
Lillian Su
Children's National Health System
Beyond Leadership: Creating High Performance Medical Teams

Pilot Awards for Projects in HIV/AIDS and Mental Health, Substance Use, and Behavioral Science (Cycle V)

Name
Institution
Project Title
Zhihuan Huang
Georgetown University
Drug use and their associations with HIV risks among female streetwalkers and their clients in Shanghai, ChinaHIV-infected older adults: a pilot study using fMRI among a high risk, community-based sample in DC
Ricardo LaGrange
Children's National Health System
SmAART: A Novel mHealth Approach to Promote HIV Management with Substance Abusing Adolescents
Manya Mangus
George Washington University
HIV-associated neurocognitive disorders and cognitive control among HIV-infected older adults: a pilot study using fMRI among a high risk, community-based sample in DC

Children's National Support of Existing and Ongoing Clinical and Translational Research (Cycle IV)

Name
Institution
Project Title
Laurie Conklin
Children's National Health System
Biomarker Discovery Utilizing MicroRNA (miRNA), Genomics, and Proteomics for Detection of Disease Activity and Response to Medications in Pediatric Inflammatory Bowel Disease (IBD)
Kristina Hardy
Children's National Health System
Computerized Cognitive Training with Preschool-aged Cancer Survivors
Molly Huntsman
Children's National Health System
The origin of intrinsic plasticity in epileptogenesis
Anitha John
Children's National Health System
Characterization of Hepatic Dysfunction in Patients following the Fontan Operation
Catherine Limperopolous
Children's National Health System
Quantification of Placental Structure and Function using Advanced MRI Techniques
Jeffrey Moak
Children's National Health System
Non-pharmacologic control of post-operative junctional ectopic tachycardia using AV nodal fat pad stimulation, feasibility study using an animal model.
Rachel Moon
Children's National Health System
Cultural Differences in Bed sharing Contribute to Infant Mortality Disparities
Javad Nazarian
Children's National Health System
Murine Model of Pediatric Brainstem Glioma
Mathew Sharron
Children's National Health System
Use of Anti-Platelet Compounds to Reduce Multiple Organ Dysfunction in Sepsis
Randi Streisand
Children's National Health System
Supplement to Prevention of Disease Care Behaviors in Early Adolescents with T1 Diabetes
Zohreh Tatari-Calderone
Children's National Health System
A Genomic Approach to Characterize Premature Infants at Risk for Developing Necrotizing Enterocolitis.
Adeline Vanderver
Children's National Health System
Molecular Mechanisms of Vanishing White Matter disease
Irene Zohn
Children's National Health System
The role of p38IP in axial skeleton defects
 

2011

KL2 (Cycle III)

Name
Institution
Project Name
Larissa May
George Washington University
Antimicrobial Stewardship through MRSA Diagnosis in ED Patients with Abscesses
Qing Pan
George Washington University
Genetic Disparities Associated with Nephropathy, Retinopathy and Neuropathy in Type 1 Diabetes Patients

Pilot Projects (Cycle III)

Name
Institution
Project Name
Amanda Castel
George Washington University
Formative Research to Assess the Acceptability and Uptake of Pre-Exposure Prophylaxis (PrEP) with Antiretrovirals for HIV Prevention among Persons at High- Risk for HIV
Michael Compton
George Washington University
A Community-Engaged Pilot Project to Prepare for Larger-Scale Anti-Stigma Schizophrenia Research
Ivor Horn
Children's National Health System
Piloting Mobile Technology to Enhance Parent Provider Communication and Improve Asthma Care
Katherine Kelly
Children's National Health System
Partnership for Academic Support and Success: PASS
Rachel Moon
Children's National Health System
Acceptability of Educational Videos Delivered via an Electronic Patient Portal
Earl Parrish
George Washington University
Formative Research to Develop a Systematic Approach for Sentiment Analysis as a Community Engagement Tool for Translation of Clinical Research and Public Health Interventions

Pilot Projects (Cycle II)

Name
Institution
Project Title
Ali Ramezani
George Washington University
Anti-HIV-1 Erythrocyte Viral Trap
Marc Siegel
George Washington University
Genomic Analysis of Respiratory Pathogens
Xiaofang Wu
Children's National Health System
In vitro Models of Glandular Hyperplasia from Basal Cells in Pediatric Chronic Rhinosinusitis
Irene Zohn
Children's National Health System
Identification of modifiers of iron deficiency induced neural tube defects

KL2 (Cycle II)

Name Institution Project Title
Brian Kirmse Children's National Health System The Effects of Antiretroviral Therapy on Energy Metabolism in Children

 

2010

Pilot Projects (Cycle I)

Name
Insitution
Project Title
Anamaris Colberg-Poley
Children's National Health System
Alteration of neural precursor cell functions by human cytomegalovirus
Robert Freishtat
Children's National Health System
Dyssynchronous Mitosis and Inflammation in Asthmatic Epithelium
Yetrib Hathou
Children's National Health System
HTRA1 as a new target for treatment of muscular dystrophies
Monica Hubal
Children's National Health System
Genetic influences on depot-specific adipose tissue remodeling with obesity
Lauren Kenworthy
Children's National Health System
Parsing Genetic Heterogeneity in Autism with Continuous Flexibility Measures
Catherine Klein
Children's National Health System
Electronic Intervention to Improve Health Behaviors in African American College Students (EI-AACS)
Andrew Meltzer
George Washington University
H. pylori testing for patients with non-specific abdominal pain in the Emergency Department
Javad Nazarian
Children's National Health System
Clinical and Translational Approaches for Understanding Pediatric Brian Tumors
Travis O'Brien
George Washington University
Genetic Factors Associated with Ovarian Hyperstimulation Syndrome
Diego Preciado
Children's National Health System