What is this resource?
*PLEASE NOTE: CURRENTLY THE FOLLOWING RESOURCES ARE ONLY AVAILABLE FOR FEASIBILITY AND COHORT DISCOVERY. THEY ARE NOT YET AVAILABLE FOR RECRUITMENT PURPOSES. APPROVAL OF AN "HONEST BROKER" PROCESS TO ENABLE RECRUITMENT IS PENDING.
i2b2, or Informatics for Integrating Biology & the Bedside, is an NIH-funded scalable informatics framework that links data warehouses across partner institutions. Locally, i2b2 facilitates exploration and query of the clinical data within PowerChart that has been de-identified and aggregated. In doing so, i2b2 helps with study feasibility and cohort discovery by allowing a researcher to query various inclusion/exclusion criteria, as well as ascertain the potential for recruitment.
The ACT Network (SHRINE) is a real-time platform allowing researchers to explore and validate feasibility for clinical studies across the NCATS Clinical and Translational Science Award (CTSA) consortium, from their desktops. The ACT Network (SHRINE) helps researchers design and complete clinical studies, and is secure, HIPAA-compliant and IRB-approved. The ACT Network leverages SHRINE, or the Shared Health Research Information Network, to support multi-site research projects by enabling study feasibility/cohort discovery at partnered institutions.
At Children’s National Health System both i2b2 and the ACT Network (SHRINE) are support by the CTSI-CN's INformatic System for Integrating Genomics, Health and Translational Sciences (INSIGHTS) program.
Note: As both tools currently only allow access to de-identified, aggregate data no IRB approval is required.
Who can use this resource?
All Children’s National Health System research faculty and staff can utilize i2b2 and the ACT Network (SHRINE).
How much does access to this resource cost?
i2b2 and the ACT Network (SHRINE) are offered at no cost. To see the cost of other CTSI-CN resources, please visit SPARC Request.
How do I access this resource?
To learn more and to register for i2b2 and the ACT Network (SHRINE) please visit: INSIGHTS System Access Request
To request direct assistance or information regarding i2b2/ACT Network (SHRINE), please register for a “Participant Recruitment Strategy and Support" Consultation via SPARC Request.
Who should I contact for more information?
To learn more, please contact the INSIGHTS Support Team at INSIGHTS@childrensnational.org.