Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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  • Mar
    26
    Tue, 03/26/2019 - 10:00 to 15:00


    Python is a popular programming language and is considered by many to be straightforward yet flexible. This workshop will introduce participants to programming by using Python to focus on the basic concepts that all programming languages build upon, and will also introduce participants to working with and visualizing data in Python, using the Pandas library. 

  • Mar
    28
    Thu, 03/28/2019 - 12:00 to 14:00


    Investigators, research staff, and graduate students are invited to explore many aspects of implicit bias in health research and examine case studies as a group. Lunch will be provided. Register early as space is limited. WebEx will be provided. 

  • Apr
    1
    Mon, 04/01/2019 (All day) to Fri, 04/05/2019 (All day)
    Each year, Children’s Research Institute (CRI), the academic arm of Children’s National Health System, showcases the scholarly achievements of our faculty, staff and trainees across all disciplines and the role they play in advancing medical science and providing the highest quality care for children. 
  • Apr
    3
    Wed, 04/03/2019 - 13:15 to 14:30
     
    Dr. Stephen Thomas and Tonya Vidal Kinlow will moderate a panel discussion on Advancing Health Equity Through Policy and Advocacy with Drs. Leandra Godoy, Shilpa Patel, Yolandra Hancock, and Kavita Parikh. Lunch will be provided for those who register in advance. WebEx is available. 
  • Apr
    8
    Mon, 04/08/2019 - 08:00 to 15:00


    This event will focus on catalyzing new collaborations to bridge the translational science, cooperative extension and other sectors to improve rural health and achieve health equity. 

  • Apr
    8
    Mon, 04/08/2019 - 12:00 to 13:00


    Dee Henderson of PR & Marketing will discuss How to Package Yourself: What's on that bio? Kevin Grigsby of the AAMC will discuss team communication and conflict resolution as part of the WATCH Seminar Series. 

  • Apr
    9
    Tue, 04/09/2019 (All day) to Wed, 04/10/2019 (All day)
    GW Research Days showcases Research, Scholarship and Creative Endeavor at the George Washington University. 
  • Apr
    10
    Wed, 04/10/2019 - 11:00 to 12:30


    The University of Illinois grant program, the Military Families Learning Network, is sponsoring a series of free webinars for professionals working with families of young children with disabilities. The target audience is early interventionists and early childhood special educators.

  • Apr
    11
    Thu, 04/11/2019 - 07:45 to 17:30


    Register early for the 29th Annual Pediatric Neurology Update. This year, the course will feature understandings and pre-requisites for an "Autism-Friendly Hospital" among other topics.

  • Apr
    11
    Thu, 04/11/2019 - 10:00 to 12:00
    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities.
  • Apr
    11
    Thu, 04/11/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • Apr
    12
    Fri, 04/12/2019 - 10:00 to 12:00
    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities. 
  • Apr
    29
    Mon, 04/29/2019 - 10:00 to 15:00
    Plan ahead for the Annual Spring Regulatory Update, co-hosted by the Clinical and Translational Science Institute at Children's National (CTSI-CN) and the Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS). 
  • May
    9
    Thu, 05/09/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • May
    16
    Thu, 05/16/2019 - 10:00 to 12:00


    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities.

  • March 21st, 2019
         
    Save the date: The annual symposium highlights the partnership between Children's National and the National Institute of Allergy and Infectious Diseases (NIAID) around four key studies being conducted at Children's National. This year, the symposium will be held on November 8, 2019 at the NIH Natcher Conference Center. More details to follow. 
  • March 18th, 2019


    An NCATS program under NIH's HEAL Initiative, A Specialized Platform for Innovative Research Exploration (ASPIRE), is accepting applications until May 31. Program information can be found here. Interested parties can watch an informational video here

  • March 18th, 2019


    In 2016, Nikki Posnack earned a pilot during award from CTSI-CN and earned her first R01 from the NHLBI in 2018. Helping scientists transition from early-stage to independent investigator is a key CTSA program goal. Read more about Dr. Posnack's work and journey here.

  • March 14th, 2019


    PRIDE is accepting applications until all spots are filled for these summer programs. If you know of colleagues who would benefit from this innovative research training and mentorship opportunity, we urge you to encourage them to apply.

  • March 13th, 2019


    Sign up soon to join a team for the annual CTSI-CN Hackathon from 1:00 - 5:30 pm on Friday, March 29. Team participation is open to all faculty/staff of Children's National and George Washington. 

  • February 27th, 2019
    Save the date: Saturday, June 1, CLIC will host an Un-Meeting on Machine Learning and Artificial Intelligence in Rochester, NY. More details to come. 
  • February 27th, 2019

    The AAMC (Association of American Medical Colleges) Early Career Women Faculty Leadership Development Seminar will take place July 27 - 30, 2019, at the Ritz-Carlton in St. Louis, Missouri.

  • February 27th, 2019

    The Training Program in Hematology for postdoctoral fellows provides experience in hematology, immunology, critical care, cardiology and nephrology and transfusion medicine with a focus on immunology (including cellular therapy), immunobiology and thrombosis research. Trainees work on projects in the laboratories of leading investigators at Children’s National, George Washington University, Howard University, and the National Institute of Health. 

  • February 21st, 2019
    The CTSI-CN Community Advisory Board (CAB), part of the CTSI-CN Community Engagement Module, is available to consult with investigators, facilitating linkages between communities and researchers in all stages of the investigative process. This program is free to investigators. Requests can be submitted through SPARC (https://sparc.ctsicn.org). 
  • February 20th, 2019
    Dr. Brian Glancy of NHLBI and NIAMS will visit Children's National on February 21st to discuss The Muscle Mitochondrial Reticulum. 
  • February 12th, 2019
    Clinical investigators are invited to the CTSI-CN clinical research unit for a series of focus groups. We want to hear what you need from us. 
  • February 7th, 2019


    The ten finalists have been announced for the 2019 CTSI-CN Hackathon. Read more and register to attend here

  • February 5th, 2019

    While the overall success rate of all NIH LRP applicants from 2006-2017 is an impressive ~50% across all NIH ICs, the success rate of CTSA Program KL2 Scholar applicants is even more notable: nearly 79% – a stat that may surprise many early career researchers. Read more here
  • January 18th, 2019
    Martin Luther King Jr. day has become a recognized day of service. Click here to learn where you can serve. 
  • January 17th, 2019
    In today's blog, NIH Director Dr. Francis Collins discusses how NIH researchers are pairing AI analysis with smartphone cameras to help more women avoid cervical cancer. Read the full article HERE.  

Impact

Has the CTSI-CN has supported your research? Tell us about it here.  

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