Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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  • Dec
    17
    Mon, 12/17/2018 - 13:00
    Catherine Stoodley, DPhil will discuss The Cerebellum and Autism: Structure, Function, and Translation. 
  • Dec
    17
    Mon, 12/17/2018 - 16:00 to 17:00
    Come join the SCIENCE team for fun science activities, art projects and health learning fun for kids and thier caregivers. 
  • Dec
    18
    Tue, 12/18/2018 - 12:00 to 13:00
    Join us for a meaningful conversation about the implementing non-sedated procedural pain management. 1.0 CNE provided. 
  • Jan
    10
    Thu, 01/10/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • Feb
    14
    Thu, 02/14/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • Mar
    14
    Thu, 03/14/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • Apr
    11
    Thu, 04/11/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • May
    9
    Thu, 05/09/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • Jun
    13
    Thu, 06/13/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • December 14th, 2018

    The faculties of Children's National Health System and George Washington, Howard, and Georgetown universities can apply for the District of Columbia Intellectual and Developmental Disabilities Research Center (DC-IDDRC) pilot award. 

  • December 7th, 2018

    The Pilot and Translational Clinical (PTC) Studies module of the CTSI-CN announces the release of the 2019-2020 RFAs.  All high impact research relevant to health and well-being throughout the lifespan is eligible. Support is not limited to pediatric research. Letters of Intent are due January 4, 2019.

  • December 3rd, 2018
    The CD2H is excited to announce the launch of the CD2H Idea Competition. This is an opportunity to turn your scientific question into a DREAM Challenge to be tackled by teams around the world. If your idea is selected, you will receive a $100,000 subcontract to run the DREAM Challenge in collaboration with the CD2H. The deadline to submit your initial proposal is February 15, 2019. 
  • December 3rd, 2018

    The George Washington University is offering an online, 3-credit-hour, 30-CME course, Grantsmanship in Clinical and Translational Research. This 10-week course begins January 14, 2019 and will cover the complete process of research grant proposal development, from specific aims to preparation of a full proposal package for submission, with the NIH R01 as exemplar.

  • November 20th, 2018

    "In April 2018, NIH launched the HEAL (Helping to End Addiction Long-term) Initiative, an aggressive, trans-agency effort to speed scientific solutions to stem the national opioid public health crisis”. The HEAL website has listed funding opportunities that will become available in December.  

  • November 7th, 2018
    The CTSI-CN proudly announces the 2019 Healthcare Hackathon. You don't have to be a programmer to have an idea for healthcare software. Finalists will attend a half-day hackathon to develop their ideas into prototypes. Winners receive funding to bring their app to life. Ideas are due January 4, 2019.
  • October 23rd, 2018
     
    Volunteers needed for Discover SCIENCE with Dr. Bear, a series of free STEAM events at DC libraries this fall and winter. Children are invited to do science activities, art projects, and learn about health. Volunteers will engage attendees in conversation about science topics and assist with activites. 
  • October 17th, 2018

    The Collaboration and Multidisciplinary Team Science (CMTS) module of the CTSI-CN announces the FALL 2018 Voucher Award Program. Multiple awards (≤ $4K each) are available for “shovel-ready” projects that will lead to paper and/or proposal submissions within 6 months of the award. All high impact research relevant to health and well-being throughout the lifespan is eligible. Support is not limited to pediatric research. Applications are due November 27, 2018

  • September 25th, 2018

    NIH considers extension requests for Early Stage Investigators (ESI) on a case-by-case basis for medical concerns, disability, extended periods of clinical training, natural disasters, and active duty military service. Effective immediately, NIH will approve an ESI extension of one year for childbirth within the ESI period. Learn more about the policy change HERE

  • September 25th, 2018
    The NIH Office of Clinical Research is offering a free, online, self-paced course.  The course runs from October 1, 2018 through June 20, 2019. Click the title for additional details. 
  • September 24th, 2018

    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 

  • September 21st, 2018

    The Board of Visitors is accepting Letters of Intent from Children's National staff. Letters are due by October 1, 2018

  • September 20th, 2018
    Starting next week, George Washington University's Office of Sponsored Projects is offering a fall series of award management trainings from pre- to post-award on a variety of focused topics. Click the title to learn more and register. 
  • September 12th, 2018

    Applications are due September 21 for funded travel to and attendance at the mobilize workshop, Rapid Biomedical Knowledge Base Construction from Text, at Stanford University. The November workshop is free to attend, but space is limited.

  • September 12th, 2018

    The Science of Team Science conference is the annual international forum dedicated to bringing together thought leaders and practitioners from a broad range of disciplines, fields, and professions. Click the title above to learn more, including the abstract submission and registration deadlines. 

Impact

Has the CTSI-CN has supported your research? Tell us about it here.  

Support Pediatric Research

Support care. Fund research. Improve lives. Children’s National takes on some of the most daunting medical research issues to improve children’s lives. Our experts develop therapies, find cures, and improve children's health in our community, across the nation, and around the world. Click here to learn more and offer your support for Pediatric Research at Children's National. Donations contribute to innovative research in a wide range of programs.