Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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Front

Events

  • Oct
    15
    Conway Chair Conversation
    Tue, 10/15/2019 - 12:00 to 13:00

    Study Replication: CHOOSE ME
    Join the Conway Chairs for a conversation on the 3rd Tuesday of each month. A themed lunch will be served. WebEx available. CNE provided. 

  • Oct
    16
    TriNetX Live Demo: Protocol Feasibility & Cohort Discovery
    Wed, 10/16/2019 - 12:00 to 14:00

    Rick Lilienthal of TriNetX will be onsite at Children's National to give an introduction to this novel platform, followed by an open forum for attendees to test drive the tool. 

  • Oct
    18
    Biostatistics Seminar Series
    Fri, 10/18/2019 - 12:00

    Scott Quinlan discusses A Tutorial on the Use of Sensitivity Analyses in Public Health Research. WebEx available. Please RSVP. 

  • Oct
    23
    Seminar 1: What is Patient-Centered Outcomes Research?
    Wed, 10/23/2019 - 12:00 to 14:00

    Subomi Akindoju of the Patient-Centered Outcomes Research Institute (PCORI) visits GW for part one of a four-part series, Developing a Patient-Centered Approach to Research in Adult Cognitive Health and Dementia. A light lunch will be provided. Please RSVP. 

  • Oct
    28
    Neuroscience Trainee-Sponsored Seminar Series
    Mon, 10/28/2019 - 13:00 to 14:00
    The Neuroscience Trainee-Sponsored Seminar Series hosts Anca Pasca, MD of Standford University. 
  • Oct
    29
    ResearchMatch Training - Free Recruitment Tool
    Tue, 10/29/2019 - 14:30 to 15:30


    ResearchMatch is an NIH-funded, national registry that brings together researchers and 140,000+ volunteers who are interested in learning more about research studies. This novel platform facilitates research participant recruitment, espcially involving surveys, rare disease, and healthy volunteers.

  • Nov
    8
    2019 Annual Children's National–NIAID Symposium
    Fri, 11/08/2019 - 08:30 to 17:00


    You are invited to the 2nd Annual Children's National-NIAID Symposium, a partnership framed & supported through the CTSI-CN. This year, the event will highlight additional research collaborations between Children's National and other institutes within NIH, and also focus on genomics and care of children with immunologic diseases. UPDATE: The draft agenda is now available. 

  • Nov
    19
    Conway Chair Conversation
    Tue, 11/19/2019 - 12:00 to 13:00

    Join the Conway Chair Conversation the 3rd Tuesday of every month. A themed lunch will be served. WebEx available. CNE provided.

  • Nov
    25
    Neuroscience Trainee-Sponsored Seminar Series
    Mon, 11/25/2019 - 13:00 to 14:00
    The Neuroscience Trainee-Sponsored Seminar Series hosts Cristina Alberini, PhD of New York University. 
  • Dec
    4
    REDCap 101 Hands-On Training: Database Design
    Wed, 12/04/2019 - 10:00 to 12:00


    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities. Would your study or research benefit from web-based data entry? REDCap might be for you!

  • Dec
    5
    REDCap 102 Hands-On Training: Surveys, Longitudinal Studies and Application
    Thu, 12/05/2019 - 10:00 to 12:00


    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities. Would your study or research benefit from web-based data entry? REDCap might be for you!

  • Dec
    17
    Conway Chair Conversation
    Tue, 12/17/2019 - 12:00 to 13:00

    Join the Conway Chair Conversation the 3rd Tuesday of every month. A themed lunch will be served. WebEx available. CNE provided.

  • Jan
    21
    Conway Chair Conversation
    Tue, 01/21/2020 - 12:00 to 13:00

    Join the Conway Chair Conversation the 3rd Tuesday of every month. A themed lunch will be served. WebEx available. CNE provided.

  • Jan
    27
    Neuroscience Trainee-Sponsored Seminar Series
    Mon, 01/27/2020 - 13:00 to 14:00
    The Neuroscience Trainee-Sponsored Seminar Series hosts Katie Drerup, PhD of NICHD. 
  • Feb
    18
    Conway Chair Conversation
    Tue, 02/18/2020 - 12:00 to 13:00

    Join the Conway Chair Conversation the 3rd Tuesday of every month. A themed lunch will be served. WebEx available. CNE provided.

More Events

News

  • New Funding Opportunities for Myasthenia Gravis
    October 10th, 2019
     
    The National Institutes of Health (NIH) awarded a research team from George Washington, Yale, and Duke Universities $7.8 million to establish a rare disease network for Myasthenia Gravis.

    Part of this funding has been made available to support two RFAs: a Scholar Program targeting clinical fellows, post-doctoral fellows, and junior faculty, a Pilot Program for faculty members. Get full details here. 
  • CTSI-CN Pilot RFAs Released
    October 4th, 2019

     

    The Pilot and Translational Clinical (PTC) Studies module of the CTSI-CN announces the release of the 2020-2021 RFAs.  All high impact research relevant to health and well-being throughout the lifespan is eligible. Support is NOT limited to pediatric research. Letters of Intent are due November 15, 2019. 

  • Boot Camp for Children's National Fellows
    September 26th, 2019

    The FDA and CTSI-CN are cosponsoring a Boot Camp for Children's National fellows. Click here to learn more. Click here to express interest. 

  • Nuts & Bolts of Successful Writing
    September 12th, 2019

        

    Eiman Abdulrahman, MD and Susan Keller, MLS invite ALL faculty and staff to attend this new writing program following the book, Essentials of Writing Biomedical Research Papers. The group will meet every other Thursday at Children's National from 1-2 pm. WebEx available. Register here. 

  • Meet the CTSI-CN
    August 27th, 2019

     

    CTSI-CN is your Research Support Center! Learn about all of our tools, resources, and services on September 11 from 12-2 pm in the Research Atrium at Children's National. More details are available here. 

  • Follow us on Twitter!
    August 19th, 2019

    Did you know CTSI-CN is on Twitter? For learn more faster, follow us at twitter.com/CTSICN. 

  • Funding available for the Clinic and Laboratory Integration Program
    July 1st, 2019
    Letters of Intent are due November 1, 2019 for the Clinic and Laboratory Integration Program (CLIP), which provides $200,000 over two years for scientists with faculty appointments. 
  • 2019 Summer Student Lecture Series
    June 20th, 2019

    This didactic lecture series covers a variety of topics including statistics in medicine, robotics, molecular medicine, mobile health apps, innovation, and clinical competency in clinical trials. These sessions are open to all summer students in CRI, SZIPSI, and Volunteer Services. 2019 Summer Student Lecture Series (pdf) 

  • NHLBI Funding Announcement
    May 29th, 2019

    Notice of Special Interest (NOSI) from NHLBI on behavioral, biological, psychosocial and/or environmental factors in infancy & earlychildhood (0-24 months) that influence obesity development. Details are available here. 

  • Proposed Rulemaking to Improve the Interoperability of Health Information
    May 21st, 2019

    The U.S. Department of Health and Human Services (HHS) recently proposed a new rule to support seamless and secure access, exchange, and use of electronic health information (EHI). Comments are due by 11:59 pm on June 3, 2019. More details are available here. Full details and related documents are here. 

  • Science Prize for Young Scientists 2019
    May 16th, 2019

    Have your PhD research published in Science magazine, win $30,000 in prize money, and travel to Sweden for the award ceremony. PhDs received in 2017 and 2018 are eligible. Apply by June 15, 2019. 

  • Women's Health In Focus
    May 8th, 2019


    Check out the latest issue of Women's Health in Focus here. The NIH Office of Research on Women's Health can be found here. 

  • National Math Festival 2019
    April 26th, 2019


    The 2019 National Math Festival has talks, performances, and activities for kids of all ages, even the grown-ups. It will be Saturday, May 4 at the Walter E. Washington Convention Center. Get all the details here: nationalmathfestival.org

  • Unpaywall offers millions of free scholarly articles
    April 25th, 2019


    Unpaywall.org is an open database of more than 25 million scholarly articles harvested from over 50,000 publishers and repositories, making it easy to find, track, and use the information that you need. 

  • Career Advancement and Leadership Skills for Women in Healthcare
    April 18th, 2019


    On April 8th, 2019, W@TCH hosted Dee Henderson, Senior PR Specialist & Science Writer, to give a lecture on how to work proactively with public relations to ace that interview, ensure your news release reaches the right reporters at the right time, and you sound and look polished and professional.

More News

Impact

How has the CTSI-CN supported your research?
Tell us about it here.  

Support Pediatric Research

Support care. Fund research. Improve lives. Children’s National takes on some of the most daunting medical research issues to improve children’s lives. Our experts develop therapies, find cures, and improve children's health in our community, across the nation, and around the world. Click here to learn more and offer your support for Pediatric Research at Children's National. Donations contribute to innovative research in a wide range of programs.