Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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Events

  • Apr
    25
    Sensory Hypersensitivity in Fragile X Syndrome: Mechanisms & Biomarkers
    Thu, 04/25/2019 - 12:00 to 13:00


    The District of Columbia Intellectual & Developmental Disabilities Research Center (DC - IDDRC) presents Dr. Khaleel Razak of the University of California Riverside. Lunch will be served. WebEx available.

  • Apr
    25
    Beyond Drug Development: The Increasing Role of Real-World Data and Real-World Evidence in Medical Research
    Thu, 04/25/2019 - 14:00 to 15:00


    The digitalization of the US healthcare system, driven by the 2014 “Meaningful Use” legislation, makes real-world data (RWD) almost infinitely available and allows the analysis of vast information representing actual medical practice. However, studies using RWD have not yet achieved the level of credibility and sophistication like randomized clinical trials (RCT) with their very detailed guidelines and regulations.

  • Apr
    27
    Discover SCIENCE Day: Breathe Easy!
    Sat, 04/27/2019 - 14:00 to 16:00


    Join us at our drop-in Family Learning Event at Shaw (Watha T. Daniel) Neighborhood Library where we will dive into the science of breathing with kids and their families.

  • Apr
    29
    Spring Regulatory Update & Hot Topics in Clinical Research
    Mon, 04/29/2019 - 10:00 to 15:00
    Plan ahead for the Annual Spring Regulatory Update, co-hosted by the Clinical and Translational Science Institute at Children's National (CTSI-CN) and the Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS). 
  • May
    1
    Attend our Seminar: PacBio SMRT Technology: Highly Accurate Long-Read Sequencing
    Wed, 05/01/2019 - 12:00 to 14:00

    PacBio is excited to announce the Sequel II System to continue delivering highly accurate long reads crucial for Human biomedical research. We will explore applications and advantages of SMRT Sequencing, now available with ~8 times the data making it more affordable for all scientists to drive discovery.

  • May
    2
    Attend our Seminar: Illumina Sequencing Technology Update & Genomics Core Users’ Presentations
    Thu, 05/02/2019 - 11:30 to 13:30


    Illumina will provide an update of their latest Next-Generation Sequencing (NGS) applications, and you’ll hear current examples of what this powerful technology is enabling GWU research to do today. Lunch is provided. Please RSVP. 

  • May
    9
    REDCap 101 Hands-On Training: Database Design
    Thu, 05/09/2019 - 10:00 to 12:00


    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities.

  • May
    9
    The Writing Institute - Natella Rakhmanina, MD
    Thu, 05/09/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • May
    10
    REDCap 102 Hands-On Training: Surveys, Longitudinal Studies and Application
    Fri, 05/10/2019 - 10:00 to 12:00


    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities.

  • May
    10
    IMPACT DC hosts a health fair on World Asthma Day
    Fri, 05/10/2019 - 12:00 to 16:00


    IMPACT DC will host a health fair in celebration of World Asthma Day on May 10, 2019. 

  • May
    15
    REDCap 101 Hands-On Training: Database Design
    Wed, 05/15/2019 - 10:30 to 12:30


    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities.

  • May
    17
    REDCap 102: Surveys, Longitudinal Studies and Application
    Fri, 05/17/2019 - 10:00 to 12:00


    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities.

  • Jun
    12
    Sunrise to Sunset: Supporting Children with Autism Through Their Day
    Wed, 06/12/2019 - 11:00 to 12:30


    The University of Illinois grant program, the Military Families Learning Network, is sponsoring a series of free webinars for professionals working with families of young children with disabilities. The target audience is early interventionists and early childhood special educators.

  • Jun
    13
    The Writing Institute - Catherine Limperopoulos, MD
    Thu, 06/13/2019 - 16:00 to 17:30
    The Writing Institute is designed to help YOU develop the habit of writing. The second Thursday of every month, a talented author from Children's National will describe how they made writing a habit. GW faculty and staff are welcome to attend. WebEx is not available. 
  • Jun
    26
    Grand Rounds & Workshop: Enhancing the Visibility of Women in Academics
    Wed, 06/26/2019 - 08:00


    Save the Date: Women @ Children's Hosptial presents Dean Angela Sharkey, MD, for a Grand Rounds presentation and workshop/networking lunch.

More Events

News

  • Career Advancement and Leadership Skills for Women in Healthcare
    April 18th, 2019


    On April 8th, 2019, W@TH hosted Dee Henderson, Senior PR Specialist & Science Writer, to give a lecture on how to work proactively with public relations to ace that interview, ensure your news release reaches the right reporters at the right time, and you sound and look polished and professional.

  • Have you met Lynda?
    April 16th, 2019

     
    Lynda.com is the training & education arm of LinkedIn. It's offered by most public libraries, and GW affiliates have access here. 

  • Funding Opportunity from DC Department of Health
    April 11th, 2019


    Applications are due April 19 to the DC Health RFA: Comprehensive Screening, Brief Intervention, and Referral to Treatment (SBIRT) Electronic Health Record Integration and Delivery. Up to 8 recipients will receive awards in amounts from $50,000 up to $112,500. Click here for the RFA. 

  • It Starts with a Spark
    April 10th, 2019


    Johnson & Johnson partnered Children's National to bring JLABS to Washington, DC! This includes the JLABS Residency. Awards will have up to $150,000 in funding. 

  • Virginia Commonwealth University Community Engagement Institute
    April 9th, 2019


    On May 14 - 15, 2019, VCU hosts the annual Community Engagement Institute, a free event that provides faculty members, community partners and graduate students the opportunity to build a fundamental understanding of the principles of community engagement in the 21st century. Learn more here. 

  • Career Advancement and Leadership Skills for Women in Healthcare
    April 8th, 2019


    Harvard Medical School invites women in healthcare to Boston, MA on November 14-16, 2019. Attendees will earn CEs while studying evidence-based strategies and skills development that help women at various career stages step into and succeed in leadership positions.

  • Children's National – NIAID Symposium 2019
    March 21st, 2019
     
    SAVE THE DATE:
    The annual symposium highlights the Children's National – NIAID partnership around four key research aims developed between the two institutions. This year, the symposium will be held on November 8, 2019 at the NIH Natcher Conference Center. More details to follow. 
  • ASPIRE Design Challenge
    March 18th, 2019


    An NCATS program under NIH's HEAL Initiative, A Specialized Platform for Innovative Research Exploration (ASPIRE), is accepting applications until May 31. Program information can be found here. Interested parties can watch an informational video here. 

  • CTSI-CN Pilot Awardee Highlighted by NCATS
    March 18th, 2019


    In 2016, Nikki Posnack earned a pilot during award from CTSI-CN and earned her first R01 from the NHLBI in 2018. Helping scientists transition from early-stage to independent investigator is a key CTSA program goal. Read more about Dr. Posnack's work and journey here.

  • Programs to Increase Diversity Among Individuals Engaged in Health-Related Research
    March 14th, 2019


    PRIDE is accepting applications until all spots are filled for these summer programs. If you know of colleagues who would benefit from this innovative research training and mentorship opportunity, we urge you to encourage them to apply.

  • You're invited to a Hackathon
    March 13th, 2019


    Sign up soon to join a team for the annual CTSI-CN Hackathon from 1:00 - 5:30 pm on Friday, March 29. Team participation is open to all faculty/staff of Children's National and George Washington. 

  • Un-Meeting on Machine Learning & Artificial Intelligence Applications In Translational Science
    February 27th, 2019
    Save the date: Saturday, June 1, CLIC will host an Un-Meeting on Machine Learning and Artificial Intelligence in Rochester, NY. More details to come. 
  • Children's National Travel Award
    February 27th, 2019

    The AAMC (Association of American Medical Colleges) Early Career Women Faculty Leadership Development Seminar will take place July 27 - 30, 2019, at the Ritz-Carlton in St. Louis, Missouri.

  • T32 Training Program in Hematology
    February 27th, 2019

    The Training Program in Hematology for postdoctoral fellows provides experience in hematology, immunology, critical care, cardiology and nephrology and transfusion medicine with a focus on immunology (including cellular therapy), immunobiology and thrombosis research. Trainees work on projects in the laboratories of leading investigators at Children’s National, George Washington University, Howard University, and the National Institute of Health. 

  • CTSI-CN Community Advisory Board (CAB) Consultation
    February 21st, 2019
    The CTSI-CN Community Advisory Board (CAB), part of the CTSI-CN Community Engagement Module, is available to consult with investigators, facilitating linkages between communities and researchers in all stages of the investigative process. This program is free to investigators. Requests can be submitted through SPARC (https://sparc.ctsicn.org). 
More News

Impact

Has the CTSI-CN has supported your research? Tell us about it here.  

Support Pediatric Research

Support care. Fund research. Improve lives. Children’s National takes on some of the most daunting medical research issues to improve children’s lives. Our experts develop therapies, find cures, and improve children's health in our community, across the nation, and around the world. Click here to learn more and offer your support for Pediatric Research at Children's National. Donations contribute to innovative research in a wide range of programs.