Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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CTSI-CN Leadership Statement

The CTSI-CN offers our heartfelt condolences to the family of George Floyd and all victims of racism and prejudice. Our mission is to advance the health and well-being of our community, including its minority and underserved populations.

We will listen, we will learn, and we will think creatively about how research initiatives can help move us towards solutions.

Most importantly, we will not turn away. We will be present to support our researchers and our communities through this difficult time in our city and our nation.

Events

  • Mar
    4
    The Anatomy of A Successful Manuscript
    Thu, 03/04/2021 - 10:00 to 11:00

    Join Dr. Sidawy on Mar 4 at 10am EST for "The Anatomy of A Successful Manuscript." This virtual event is hosted by the Clinical and Translational Science Institute at Children's National (CTSI-CN). This seminar will provide research trainees the necessary tools to prepare, submit, and successfully publish a manuscript. Target Audience: Research Trainees and Investigators in Health Sciences.

  • Mar
    4
    Genomics Data Carpentry Workshop: Session 1 of 4
    Thu, 03/04/2021 - 13:00 to 17:00

    Join us for these 4 afternoons of hands-on instruction in fundamental data skills that help you save time and increase research quality! Participants must register ahead of time and attend for all 4 afternoons.

  • Mar
    5
    Genomics Data Carpentry Workshop: Session 2 of 4
    Fri, 03/05/2021 - 13:00 to 17:00

    Join us for these 4 afternoons of hands-on instruction in fundamental data skills that help you save time and increase research quality! Participants must register ahead of time and attend for all 4 afternoons.

  • Mar
    8
    W@tCH (Women @ Children's Hospital)
    Mon, 03/08/2021 - 18:00 to 19:30

    "Diversity, Equity, and Inclusion" with Denice Cora-Bramble, MD, MBA and Yoland

  • Mar
    11
    JLABS Webinar Series
    Thu, 03/11/2021 - 12:00 to 13:00

    "In Celebration of Women’s History Month: Closing the Gap in Access to Capital"

  • Mar
    11
    Genomics Data Carpentry Workshop: Session 3 of 4
    Thu, 03/11/2021 - 13:00 to 17:00

    Join us for these 4 afternoons of hands-on instruction in fundamental data skills that help you save time and increase research quality! Participants must register ahead of time and attend for all 4 afternoons.

  • Mar
    12
    Genomics Data Carpentry Workshop: Session 4 of 4
    Fri, 03/12/2021 - 13:00 to 17:00

    Join us for these 4 afternoons of hands-on instruction in fundamental data skills that help you save time and increase research quality! Participants must register ahead of time and attend for all 4 afternoons.

  • Mar
    26
    Omics Data Data Science Workshop: Downstream Analysis and Biomarker Discovery
    Fri, 03/26/2021 - 09:00 to 15:00

    Participants will gain hands-on experience with these analyses using tools for pattern discovery in multi-omics. Interspersed with lecture content, attendees will work through multi-omics analysis exercises with real data. Participants are strongly encouraged to bring their own data and study examples for application.

  • Apr
    12
    11th Annual Research, Education, and Innovation (REI) Week: April 12-16, 2021
    Mon, 04/12/2021 (All day) to Fri, 04/16/2021 (All day)

    Submit your abstracts by 12 noon on January 11, 2021!

  • Apr
    12
    GW Research Showcase: April 12-16, 2021
    Mon, 04/12/2021 (All day) to Fri, 04/16/2021 (All day)

    GW Research Showcase, previously GW Research Days, highlights the breadth of innovation and creativity being conducted at GW across all disciplines. Students, undergraduate and graduate, are invited to present their work and compete for prize money. Due to COVID-19 and the continued remote learning, GW Research Showcase 2021 is being planned as a virtual event.

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News

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ICAN DC Chapter: Join Us!

The International Children's Advisory Network, Inc., (iCAN) is a worldwide consortium of children’s advisory groups that work in unison around the world to provide a voice for children and families in medicine, research, and innovation. 

 

The DC Chapter focuses on providing children with past clinical experience, experience using hospital services, chronic medical conditions and/or take medication regularly, and/or an interest in medicine and/or research, opportunities to share their experience with key stakeholders and learn more about child health.

 

Learn more