Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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Events

  • Jun
    17
    Chasing a Moving Target: Challenges of Evaluating the Late Effects of Childhood Cancer
    Mon, 06/17/2019 - 09:00

    Kristina K. Hardy, PhD will discuss the Challenges of Evaluating the Late Effects of Childhood Cancer. A themed lunch will be served. WebEx available. CNE provided.

  • Jun
    17
    CTSI-CN Annual Resource Symposium
    Mon, 06/17/2019 - 13:00 to 15:00

    CTSI-CN is research support! Learn about the wide variety of CTSI-CN services and resources available to researchers at Children's National and George Washington. WebEx is available. RSVP to Grants Enhancement. 

  • Jun
    18
    Health Workforce Equity Summit
    Tue, 06/18/2019 - 13:00 to 17:00

    As the keynote speaker, Leana Wen, President of Planned Parenthood and prior GW faculty member, will discuss Workforce Challenges to Achieving Reproductive Health Access & Equity. 

  • Jun
    19
    TriNetX: I Came, I Saw, I Validated: Using Real-World Data to Verify Clinical Guidelines & Black Box Warnings
    Wed, 06/19/2019 - 14:00 to 15:00


    Please join us to learn more about utilizing RWD for validation of clinical practice recommendations and how combining the data and analytics platform available from TriNetX helped advance this research.

  • Jun
    20
    The NIH/CDC Sudden Death in the Young Case Registry
    Thu, 06/20/2019 - 07:00 to 08:00
    Please join the Children's National Heart Institute to learn about "The NIH/CDC Sudden Death in the Young Case Registry". 
  • Jun
    26
    Grand Rounds & Workshop: Enhancing the Visibility of Women in Academics
    Wed, 06/26/2019 - 08:00


    Save the Date: Women @ Children's Hosptial presents Dean Angela Sharkey, MD, for a Grand Rounds presentation and workshop/networking lunch.

  • Jul
    22
    REDCap 101 Hands-On Training: Database Design
    Mon, 07/22/2019 - 11:00 to 13:00


    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities. July trainings will be held at Children's National, West Wing, P2 level in Technology Training Room 1.

     

  • Jul
    23
    REDCap 102: Surveys, Longitudinal Studies and Application
    Tue, 07/23/2019 - 13:00 to 15:00


    The Clinical and Translational Science Institute at Children's National (CTSI-CN) is pleased to continue to offer Research Electronic Data Capture (REDCap) training to the Children's National and GW research communities. July trainings will be held at Children's National, West Wing, P2 level in Technology Training Room 1.

     

  • Nov
    8
    Children's National – NIAID Symposium 2019
    Fri, 11/08/2019 - 08:00 to 17:00
         
    Save the date: This annual symposium highlights the partnership between Children's National and the National Institute of Allergy and Infectious Diseases (NIAID) around four key studies being conducted at Children's National. This year, the symposium will be held at the NIH Natcher Conference Center. More details to follow. 
More Events

News

  • NHLBI Funding Announcement
    May 29th, 2019

    Notice of Special Interest (NOSI) from NHLBI on behavioral, biological, psychosocial and/or environmental factors in infancy & earlychildhood (0-24 months) that influence obesity development. Details are available here. 

  • Proposed Rulemaking to Improve the Interoperability of Health Information
    May 21st, 2019

    The U.S. Department of Health and Human Services (HHS) recently proposed a new rule to support seamless and secure access, exchange, and use of electronic health information (EHI). Comments are due by 11:59 pm on June 3, 2019. More details are available here. Full details and related documents are here. 

  • Science Prize for Young Scientists 2019
    May 16th, 2019

    Have your PhD research published in Science magazine, win $30,000 in prize money, and travel to Sweden for the award ceremony. PhDs received in 2017 and 2018 are eligible. Apply by June 15, 2019. 

  • Women's Health In Focus
    May 8th, 2019


    Check out the latest issue of Women's Health in Focus here. The NIH Office of Research on Women's Health can be found here. 

  • National Math Festival 2019
    April 26th, 2019


    The 2019 National Math Festival has talks, performances, and activities for kids of all ages, even the grown-ups. It will be Saturday, May 4 at the Walter E. Washington Convention Center. Get all the details here: nationalmathfestival.org

  • Unpaywall offers millions of free scholarly articles
    April 25th, 2019


    Unpaywall.org is an open database of more than 25 million scholarly articles harvested from over 50,000 publishers and repositories, making it easy to find, track, and use the information that you need. 

  • Career Advancement and Leadership Skills for Women in Healthcare
    April 18th, 2019


    On April 8th, 2019, W@TCH hosted Dee Henderson, Senior PR Specialist & Science Writer, to give a lecture on how to work proactively with public relations to ace that interview, ensure your news release reaches the right reporters at the right time, and you sound and look polished and professional.

  • Have you met Lynda?
    April 16th, 2019

     
    Lynda.com is the training & education arm of LinkedIn. It's offered by most public libraries, and GW affiliates have access here. 

  • Funding Opportunity from DC Department of Health
    April 11th, 2019


    Applications are due April 19 to the DC Health RFA: Comprehensive Screening, Brief Intervention, and Referral to Treatment (SBIRT) Electronic Health Record Integration and Delivery. Up to 8 recipients will receive awards in amounts from $50,000 up to $112,500. Click here for the RFA. 

  • It Starts with a Spark
    April 10th, 2019


    Johnson & Johnson partnered Children's National to bring JLABS to Washington, DC! This includes the JLABS Residency. Awards will have up to $150,000 in funding. 

  • Virginia Commonwealth University Community Engagement Institute
    April 9th, 2019


    On May 14 - 15, 2019, VCU hosts the annual Community Engagement Institute, a free event that provides faculty members, community partners and graduate students the opportunity to build a fundamental understanding of the principles of community engagement in the 21st century. Learn more here. 

  • Career Advancement and Leadership Skills for Women in Healthcare
    April 8th, 2019


    Harvard Medical School invites women in healthcare to Boston, MA on November 14-16, 2019. Attendees will earn CEs while studying evidence-based strategies and skills development that help women at various career stages step into and succeed in leadership positions.

  • Children's National – NIAID Symposium 2019
    March 21st, 2019
     
    SAVE THE DATE:
    The annual symposium highlights the Children's National – NIAID partnership around four key research aims developed between the two institutions. This year, the symposium will be held on November 8, 2019 at the NIH Natcher Conference Center. More details to follow. 
  • ASPIRE Design Challenge
    March 18th, 2019


    An NCATS program under NIH's HEAL Initiative, A Specialized Platform for Innovative Research Exploration (ASPIRE), is accepting applications until May 31. Program information can be found here. Interested parties can watch an informational video here. 

  • CTSI-CN Pilot Awardee Highlighted by NCATS
    March 18th, 2019


    In 2016, Nikki Posnack earned a pilot during award from CTSI-CN and earned her first R01 from the NHLBI in 2018. Helping scientists transition from early-stage to independent investigator is a key CTSA program goal. Read more about Dr. Posnack's work and journey here.

More News

Impact

Has the CTSI-CN has supported your research? Tell us about it here.  

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