Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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Front

  • Sep
    26
    Wed, 09/26/2018 - 11:00 to 14:00

    Guest speaker from IDC Research, Gary Chen will discuss why organizations are turning to container platforms. 

  • Oct
    2
    Tue, 10/02/2018 - 12:00 to 13:00

    Alla Keselman, PhD will be speaking at our Informatics Seminar. Dr. Keselman is a senior social science analyst in the NIH National Library of Medicine’s Division of Specialized Information Services (SIS).

  • Oct
    3
    Wed, 10/03/2018 - 12:00 to 13:00

    Driving precision medicine through biostatistics: Translating multiomics biomarker data into breakthrough knowledge

  • Oct
    4
    Thu, 10/04/2018 - 15:00 to 16:00
    Join BRANY (Biomedical Research Alliance of New York), the creator of Protocol Builder for a free advanced-level webinar/live demo of this novel protocol development tool. Primarily developed for Residents and New Investigators (but open to all users), this session will focus on advanced features including References Library import from external sources, advanced collaboration features, and summary of changes.
  • Oct
    10
    Wed, 10/10/2018 - 13:00 to 14:00

    Get the basics on ResearchMatch and i2b2 and use them for Cohort discovery and Recruitment. You have free access to these tools through the CTSI-CN. 

  • September 12th, 2018

    Applications are due September 21 for funded travel to and attendance at the mobilize workshop, Rapid Biomedical Knowledge Base Construction from Text, at Stanford University. The November workshop is free to attend, but space is limited.

  • September 12th, 2018

    The Science of Team Science conference is the annual international forum dedicated to bringing together thought leaders and practitioners from a broad range of disciplines, fields, and professions. Click the title above to learn more, including the abstract submission and registration deadlines. 

  • September 10th, 2018
    Experts from FDA’s Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), Center for Devices and Radiological Health (CDRH), the University of Maryland, and the University of Pennsylvania will provide a deep dive into the scientific background and practical methodology needed when conducting clinical trials.
  • September 4th, 2018
    The purpose of this contest is to find the best ideas in all of CTSA-land for encouraging better team science. Any person associated with a CTSA hub is eligible. Click the title above to learn more. 
  • June 7th, 2018

    Translating Translation "NCATS is unique at NIH in that the name in the Center’s mission — “translation” — has a firmly
    established meaning that is generally associated with languages, not biomedical research. By contrast, other NIH
    components are named for widely known medical problems, such as cancer, diabetes and stroke." 

Impact

Has the CTSI-CN has supported your research? Tell us about it here.  

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