Basic Research
Basic research involves scientific exploration that can reveal fundamental mechanisms of biology, disease or behavior. Every stage of the translational research spectrum builds upon and informs basic research. NCATS scientists typically do not conduct basic research; however, insights gained from the Center’s studies along the translational spectrum can inform basic research.
Pre-Clinical Research
Pre-clinical research connects the basic science of disease with human medicine. During this stage, scientists develop model interventions to further understand the basis of a disease or disorder and find ways to treat it. Testing is carried out using cell or animal models of disease; samples of human or animal tissues; or computer-assisted simulations of drug, device or diagnostic interactions within living systems.
Clinical Research
Clinical research includes studies to better understand a disease in humans and relate this knowledge to findings in cell or animal models; testing and refinement of new technologies in people; testing of interventions for safety and effectiveness in those with or without disease; behavioral and observational studies; and outcomes and health services research. The goal of many clinical trials is to obtain data to support regulatory approval for an intervention.
Clinical Implementation
The clinical implementation stage of translation involves the adoption of interventions that have been demonstrated to be useful in a research environment into routine clinical care for the general population. This stage also includes implementation research to evaluate the results of clinical trials and to identify new clinical questions and gaps in care.
Public Health
In this stage of translation, researchers study health outcomes at the population level to determine the effects of diseases and efforts to prevent, diagnose and treat them. Findings help guide scientists working to assess the effects of current interventions and to develop new ones.
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CTSI-CN Leadership Statement

The CTSI-CN offers our heartfelt condolences to the family of George Floyd and all victims of racism and prejudice. Our mission is to advance the health and well-being of our community, including its minority and underserved populations.

We will listen, we will learn, and we will think creatively about how research initiatives can help move us towards solutions.

Most importantly, we will not turn away. We will be present to support our researchers and our communities through this difficult time in our city and our nation.

  • Apr
    Mon, 04/12/2021 (All day) to Fri, 04/16/2021 (All day)

    Submit your abstracts by 12 noon on January 11, 2021!

  • Apr
    Mon, 04/12/2021 (All day) to Fri, 04/16/2021 (All day)

    GW Research Showcase, previously GW Research Days, highlights the breadth of innovation and creativity being conducted at GW across all disciplines. Students, undergraduate and graduate, are invited to present their work and compete for prize money. Due to COVID-19 and the continued remote learning, GW Research Showcase 2021 is being planned as a virtual event.

  • Apr
    Mon, 04/12/2021 (All day) to Fri, 04/16/2021 (All day)

    In collaboration with Children’s National Hospital (CNH) pediatric residency program, this introductory course highlights several areas of global health practice. Specific core content such as Global Health Policy, Emergency Triage and Treatment, Ethics, Malaria and HIV are supplemented by timely and relevant topics. Contributors to the course include GHI and CNH core faculty, as well as programs such as USAID, Save the Children, Doctors without Border, Johns Hopkins, and more.

  • Apr
    Wed, 04/14/2021 (All day) to Fri, 04/16/2021 (All day)

    The George Washington University is hosting its inaugural Digital Health Summit focused on the rapid acceleration of digital technologies in healthcare and the implications for healthcare and academic environments alike.

  • Apr
    Fri, 04/23/2021 - 11:00 to 12:00

    "Mentorship Challenges: Making the Best of Complicated Relationships"

The National Institutes of Health launched the National COVID Cohort Collaborative (N3C) Data Enclave, and researchers studying COVID-19 can apply to access this innovative new analytics platform containing clinical data from the electronic health records of people who were tested for the novel coronavirus or who had related symptoms. This data resource will help scientists further understand the disease, including potential risk factors, protective factors and long-term health consequences. The N3C is funded by the National Center for Advancing Translational Sciences (NCATS). To get started, click here.